Efficacy of Controlled Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy (HIE)
This study aims to evaluate the effectiveness of therapeutic hypothermia in neonates diagnosed with hypoxic-ischemic encephalopathy (HIE). The study focuses on assessing both short-term outcomes after treatment and long-term neurological outcomes following therapeutic hypothermia.
• Neonates diagnosed with hypoxic-ischemic encephalopathy (HIE) at the Neonatal Center, National Children's Hospital
• Gestational age ≥ 36 weeks
• Assessed using the modified Sarnat staging within the first 0-6 hours after birth
• Eligible for and/or treated with therapeutic hypothermia according to institutional protocol
• Underwent clinical and paraclinical monitoring during hospitalization
• Received brain magnetic resonance imaging (MRI) during the neonatal period (from 5 to 17 days of age)
• Availability of complete medical records for data collection and analysis