Comparison of Short-term Glucocorticoid Monotherapy and Short-term Glucocorticoid Combined with Mycophenolate Mofetil in the Treatment of IgG4 Related Disease
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Comparison of short-term glucocorticoid monotherapy and short-term glucocorticoid combined with MMF in the treatment of IgG4 Related Disease
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• 18-80 years old;
• All patients must meet the comprehensive diagnostic criteria of IgG4-RD revised in Japan in 2020 or the classification criteria of IgG4-RD formulated by ACR/EULAR in 2019;
• Active IgG4-RD (at least one organ has an IgG4-RD reaction score \>=2 at the time of enrollment.)；
• No previous medication or recurrence after withdrawal.
Locations
Other Locations
China
Peking Union Medical College Hospital
RECRUITING
Beijing
Contact Information
Primary
Linyi Peng, MD
drpenglinyi@163.com
8615810395901
Time Frame
Start Date: 2023-09-01
Estimated Completion Date: 2025-09-01
Participants
Target number of participants: 63
Treatments
Placebo_comparator: short-term glucocorticoid monotherapy
Oral prednison starts at 0.6-0.8mg/kg/d, then tapered and withdrawal in 6 months.
Experimental: short-term glucocorticoid combined with Mycophenolate mofetil
Oral prednison starts at 0.6-0.8mg/kg/d, then tapered and withdrawal in 6 months. Oral Mycophenolate mofetil 0.75g bid for 6 months.
Related Therapeutic Areas
Sponsors
Leads: Wen Zhang