The Clinical Efficacy Study of Selective Gastrogenic Microbiota Transplantation in the Treatment of Functional Dyspepsia
Status: Recruiting
Location: See location...
Intervention Type: Other, Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Single-center prospective interventional study aimed at demonstrating the effect of gastric-origin probiotics on dyspeptic symptoms, tryptophan metabolism, and microbiome parameters in FD patients without Helicobacter pylori infection, compared to a placebo group
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:
• Adults aged ≥18 and ≤70 years, with symptoms such as upper abdominal pain or burning sensation, postprandial bloating, early satiety, etc., and who meet the diagnostic criteria for functional dyspepsia (FD) according to the Rome IV criteria.
• Negative result on the C13 urea breath test, and no organic changes observed on gastroscopy.
Locations
Other Locations
China
NanfangH
RECRUITING
Guangzhou
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 68
Treatments
Experimental: cohort 1FD
Receiving 8 weeks of Gastrogenic Microbiota
Placebo_comparator: cohort 2FD
Receiving 8 weeks of placebo
Related Therapeutic Areas
Sponsors
Leads: Nanfang Hospital, Southern Medical University