A Multi-Center, Prospective, Randomized Controlled Trial Comparing the Safety and Effectiveness of Prodisc® C SK and Prodisc® C Vivo to Mobi-C® Cervical Disc in the Treatment of Two-Level Symptomatic Cervical Disc Disease (SCDD)

Status: Active_not_recruiting
Location: See all (30) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 69
Healthy Volunteers: t
View:

• Age ≥18 and ≤69 years.

• Diagnosis of radiculopathy or myelopathy with radiculopathy of the cervical spine, with pain, paresthesias or paralysis in a specific nerve root distribution C3 through C7, including at least one of the following:

• Symptomatic cervical disc disease (SCDD) at two contiguous levels from C3 to C7.

• Radiographically determined pathology at the level to be treated correlating to primary symptoms.

• Unresponsive to non-operative, conservative treatment (rest, heat, electrotherapy, physical therapy, chiropractic care and/or analgesics)

Locations
United States
Arizona
Flagstaff Bone and Joint
Flagstaff
California
Todd Lanman, MD, Inc.
Beverly Hills
Doctors Outpatient Center for Surgery
Los Angeles
Sutter Health - Palo Alto Medical Foundation
Palo Alto
Sutter Health
Sacramento
Colorado
HCA Healthcare
Lone Tree
Sky Ridge Medical Center Campus
Lone Tree
Center for Spine and Orthopedics, Scientific Education and Research Foundation
Thornton
Washington, D.c.
Georgetown University Hospital
Washington D.c.
Florida
St. Vincent's Neurosurgery
Jacksonville
Kennedy-White Orthopaedic Center
Sarasota
University of South Florida
Tampa
Florida Orthopaedic Institute
Temple Terrace
Indiana
Indiana Spine Group
Carmel
Kentucky
Orthopaedic Institute of Western Kentucky
Paducah
Louisiana
Spine Institute of Louisiana
Shreveport
Maryland
University of Maryland Medical Center
Baltimore
Michigan
William Beaumont Hospital
Royal Oak
North Carolina
M3-Emerging Medical Resarch
Durham
New Jersey
University Spine Center
Wayne
New York
Hospital for Special Surgery
New York
Northwell Health, Lenox Hill Hospital
New York
NYU Langone Orthopedic Hospital
New York
Axis Neurosurgery and Spine
Williamsville
Ohio
SVCMC Solon Medical - Northern Ohio Surgery Center
Beachwood
Pennsylvania
Penn State Milton S. Hershey Medical Center
Hershey
Texas
DFW Center for Spinal Disorders
Fort Worth
Texas Back Institute
Plano
Texas Spine Care Center
San Antonio
Utah
The Disc Replacement Center
Salt Lake City
Time Frame
Start Date: 2019-08-05
Completion Date: 2028-05-13
Participants
Target number of participants: 390
Treatments
Experimental: Investigational
Two-level prodisc C SK and/or prodisc C Vivo
Active_comparator: Control
Two-level Mobi-C device
Related Therapeutic Areas
Sponsors
Leads: Centinel Spine

This content was sourced from clinicaltrials.gov