Venous StEnt for Idiopathic IntraCranial HypertEnsion (VEHICLE) Registry: Management and Outcomes in the MENA Region

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

The VEHICLE Registry is a multicenter observational study aimed at evaluating the management and outcomes of patients with Idiopathic Intracranial Hypertension (IIH) undergoing venous sinus stenting in the Middle East and North Africa (MENA) region. The study focuses on assessing clinical characteristics, treatment efficacy, safety, and the role of venous sinus stenting as a therapeutic modality in IIH.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 60
Healthy Volunteers: f
View:

• Adults aged 18 to 60 years.

⁃ Diagnosed with Idiopathic Intracranial Hypertension (IIH) based on the modified Dandy criteria, including:

⁃ Symptoms of increased intracranial pressure (e.g., headache, visual disturbances).

⁃ Elevated opening pressure (\>250 mm H₂O) on lumbar puncture with normal cerebrospinal fluid composition.

⁃ No evidence of intracranial pathology (e.g., mass lesion, hydrocephalus) on neuroimaging.

⁃ Presence of papilledema. Evidence of venous sinus stenosis on Magnetic Resonance Venography (MRV) or Digital Subtraction Angiography (DSA).

⁃ Refractory to medical therapy or intolerant to medications (e.g., acetazolamide).

⁃ Willingness to undergo venous sinus stenting. Provided informed consent for participation.

Locations
Other Locations
Egypt
Alexandria University
RECRUITING
Alexandria
Saudi Arabia
King Abdullah Medical City (KAMC) -
RECRUITING
Makkah Al Mukarramah
Contact Information
Primary
ossama yasssin mansour, MD, PhD
ossama.mansour@alexmed.edu.eg
+19297216189
Time Frame
Start Date: 2021-08-11
Estimated Completion Date: 2025-11-11
Participants
Target number of participants: 150
Sponsors
Leads: Middle East North Africa Stroke and Interventional Neurotherapies Organization

This content was sourced from clinicaltrials.gov