Irritable Bowel Syndrome (IBS) Clinical Trials

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Fecal Microbiota Transplantation for Irritable Bowel Syndrome Associated Food Intolerance

Status: Recruiting
Location: See location...
Intervention Type: Biological
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Previous studies have shown that stool transplantation (FMT) have positive effect in symptoms for some patients with irritable bowel syndrome (IBS). Studies have shown that it is possible by FMT to reverse the microbiome of the recipient's intestine in the direction of the microbiome of the donor. The effect on eating habits for engraftment of microbiome by FMT is unknown. The purpose of this study is to investigate whether FMT relieves FODMAP diet extension without worsening intestinal symptoms in IBS patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Adults, age 18-75 years, knowledge of the Finnish language

• IBS patients have been diagnosed with the Rome IV- criteria, all IBS-subtypes will be accepted to the trial

• The patient must consume low FODMAP diet to control IBS symptoms

• Patient must sign the informed consent

Locations
Other Locations
Finland
Helsinki University Hospital
RECRUITING
Helsinki
Contact Information
Primary
Perttu Arkkila, Professor
perttu.arkkila@hus.fi
+358504272272
Backup
Perttu Lahtinen, Md
perttu.lahtinen@phhyky.fi
+358381911
Time Frame
Start Date: 2022-04-30
Estimated Completion Date: 2026-07-31
Participants
Target number of participants: 45
Treatments
Active_comparator: FMT form healthy donor
FMT from healthy donor
Placebo_comparator: FMT plasebo
FMT plasebo
Related Therapeutic Areas
Sponsors
Collaborators: Paijat-Hame Hospital District, University of Helsinki, Turku University Hospital
Leads: Helsinki University Central Hospital

This content was sourced from clinicaltrials.gov