Evaluation of Quality of Life in a Cohort of Diarrhoeic Irritable Bowel Syndrome (IBS-D) Patients Assuming GABA.
The study aims to evaluate the impact on quality of life and abdominal discomfort of GABA and Melissa food supplement administration in patients with diarrhea-predominant irritable bowel syndrome.
• Age \> 18 years and ≤ 75
• A positive diagnosis of IBS-D according to Rome IV criteria.
• Both males and females.
• Negative relevant additional screening or consultation whenever appropriate
• Colonoscopy if there are alarm symptoms (eg. Rectal bleeding, pseudodiarrhea). If the patients' age is \> or = 50 yrs a colonoscopy within 5 years is mandatory.
• Availability to participate in the clinical study, confirmed by the signed informed consent form.
• Ability to conform to the study protocol.
• Patients' ability to complain study protocol procedures.
• Subjects who decide to use single or double contraceptive methods not to conceive during study period.