The Role of Diet and Gastrointestinal Motility in Irritable Bowel Syndrome (IBS)

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The goal of this observational study is to identify factors that influence symptoms in children with irritable bowel syndrome (IBS), to find ways to make diet treatments work better and possibly create personalized plans to help each child with IBS feel better. The main question it aims to answer is: 1. What types of food do the kids eat and how do these diets relate to their symptoms? 2. Is there any motility pattern that we can identify from the kids with or without IBS using a wearable patch? 3. What kinds of bacteria and chemicals are found in the gut and urine of children with IBS, and how are these linked to their IBS symptoms? Participants will use the wearable patch, answer questionnaires, collect stool and urine samples, and recall their 24 hours dietary.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 18
Healthy Volunteers: t
View:

⁃ Cases:

• Males and females age 8 - 18 years

• Diagnosis of irritable bowel syndrome (IBS).

• Parental/guardian permission (informed consent) and child assent

⁃ Controls:

• Males and Females age 8-18 years

• No diagnosis of abdominal pain disorder

• Parental/guardian permission (informed consent) and child assent

Locations
United States
Pennsylvania
Children's Hospital of Philadelphia
RECRUITING
Philadelphia
Contact Information
Primary
Alain Benitez, MD, MSTR
BenitezA@chop.edu
215-590-1000
Time Frame
Start Date: 2023-07-31
Estimated Completion Date: 2027-06
Participants
Target number of participants: 90
Treatments
IBS Cohort
Participants ages 8 to 18 years old who meet Rome IV diagnostic criteria for IBS
Control Cohort
Participants ageds 8-18 years old who don't have IBS
Related Therapeutic Areas
Sponsors
Leads: Children's Hospital of Philadelphia

This content was sourced from clinicaltrials.gov