Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

This is a single-centre, observational cohort study with the following objectives: Firstly, the investigators aim to evaluate the vision-related quality of life and mental health status in congenital ectopia lentis patients. Secondly, the investigators target to investigate the correlations between genotype and clinical phenotype in patients of congenital ectopia lentis. Thirdly, to explore the metabolic profiles in the aqueous humor (AH) of patients with congenital ectopia lentis. Lastly, this study aims to explore the longitudinal changes of ocular biological parameters and complications in patients with postoperative congenital ectopia lens in the Chinese population.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Healthy Volunteers: t
View:

• Diagnosed with congenital lens dislocation and age ≥ 3 years old.

• Agree to participate in this study with written informed consent from patients or legal guardians.

Locations
Other Locations
China
Guangdong Provincial Clinical Research Center for Ocular Diseases, State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science
RECRUITING
Guangzhou
Contact Information
Primary
Dangying Zheng, M.D
zhengdyy@163.com
020-87330478
Time Frame
Start Date: 2022-12-05
Estimated Completion Date: 2027-12
Participants
Target number of participants: 604
Treatments
Non-surgical group: Refractive change, ocular parameter changes, and prognosis without surgery
To evaluate the long-term changes in refractive state, ocular parameter, ocular development and visual prognosis in patients without congenital ectopia lentis surgery.
Surgical group: Safety and efficacy of different congenital ectopia lentis surgeries
To compare the safety and efficacy of different congenital ectopia lentis surgeries, including phacoemulsification, phacoemulsification + Intraocular lens (IOL) implantation, phacoemulsification + IOL implantation + Capsular Tension Ring implantation or phacoemulsification + IOL implantation + transscleral fixation.
Related Therapeutic Areas
Sponsors
Leads: Zhongshan Ophthalmic Center, Sun Yat-sen University

This content was sourced from clinicaltrials.gov

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