Spleen Stiffness Measurement Predicts Short-term Outcomes of Chronic Liver Disease Inpatients With Acute Liver Injury: a Prospective, Observational and Multicentre Study
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the effect of dynamic changes in SSM on the short-term prognosis (28-day, 90-day morbidity and mortality) of inpatients with CLD and acute liver injury.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age between 18 years and 80 years
• Chronic liver diseases regardless of etiology
• Acute liver injury with total bilirubin ≥ 3 mg/dl regardless of inducement
Locations
Other Locations
China
Hepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University
RECRUITING
Guangzhou
Contact Information
Primary
Jinjun Chen, PHD
chjj@smu.edu.cn
86-18588531001
Time Frame
Start Date: 2024-01-01
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 411
Related Therapeutic Areas
Sponsors
Leads: Nanfang Hospital, Southern Medical University