A Prospective Study: A Computer Vision Model on a Smartphone Platform for Real-time Evaluation of Serum Bilirubin Through Sclera Images

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The primary efficacy endpoints are the standard deviation and coefficient of determination (R2) between predicted and actual values for the bilirubin regression model, and the grading accuracy for the jaundice severity classification model. The secondary efficacy endpoint is the mean percentage error between predicted and actual bilirubin values. There are no relevant safety risks. Statistical differences for categorical variables (e.g., jaundice grading evaluation indicators) will be analyzed using the chi-square test or Fisher's exact probability test. For continuous variables (e.g., bilirubin prediction evaluation indicators), t-tests (normal distribution) or non-parametric tests (non-normal distribution) will be used. The 95% confidence interval for jaundice grading accuracy will be calculated using the Wilson method. The study duration is estimated to be 3 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 14
Healthy Volunteers: t
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• Age 14 years or older. Subjects who are visiting the Gastroenterology Department of Xijing Hospital and will undergo liver function tests on the same day. The disease spectrum of the subjects mainly includes pancreatitis, pancreatic tumors, hepatobiliary stones, biliary tumors, and colonic polyps.

Locations
Other Locations
China
First Affiliated Hospital of Air Force Military Medical University
RECRUITING
Xi'an
Contact Information
Primary
Yanglin Pan, MD
yanglinpan@hotmail.com
86-13991811225
Time Frame
Start Date: 2024-04-20
Estimated Completion Date: 2024-07-10
Participants
Target number of participants: 270
Treatments
Real-Time Scleral Jaundice Evaluation in Gastroenterology Cohort
The cohort consists of at least 270 subjects consecutively enrolled from the Department of Gastroenterology at Xijing Hospital. The subjects will be followed prospectively over a period of time to collect data on their age, medical information, scleral images, and liver function test results. The cohort includes patients with various liver diseases and varying degrees of jaundice severity.
Related Therapeutic Areas
Sponsors
Leads: Air Force Military Medical University, China

This content was sourced from clinicaltrials.gov