• healthy subjects with no other medical or ocular conditions

∙ Subjects who have one or both eyes that meet criteria 1 and 1 or more of the following criteria will be considered candidates for this study:

• 18 years of age or older

• Presence of central or inferior steepening (on Pentacam topograph)

• Axial topography consistent with keratoconus, post-surgical ectasia, or pellucid marginal degeneration (See keratoconus grading section 7.0 for details)

• Presence of one or more findings associated with keratoconus or pellucid marginal degeneration on slit lamp exam such as:

‣ Fleischer ring

⁃ Vogt's striae

⁃ Decentered corneal apex

⁃ Munson's sign

⁃ Rizzutti's sign

⁃ Apical Corneal scarring consistent with Bowman's breaks

⁃ Scissoring of the retinoscopic reflex

⁃ Crab-claw appearance on topography

• Steepest keratometry (Kmax) value ≥ 47.20 D on simK or Pentacam

• I-S keratometry difference \> 1.5 D on the Pentacam/Galilei/Orbscan/Cassini map or topography map

• Posterior corneal elevation \>16 microns (µm on Pentacam tomography)

• Thinnest corneal point \<485 microns (ultrasound pachymetry or Pentacam tomography)

• Predicted Post LASIK/PRK stromal ablation depth \<350 microns or expected keratometry \>47.2 D, or patients undergoing PRK/SMILE in keratoconus suspect eyes

• Bacterial or fungal corneal keratitis persistent and not responding despite \> 2 weeks of standard antimicrobial therapy or with rapid progression of corneal thinning, with loss of \>25% corneal thickness

• Contact Lens Wearers Only:

‣ Removal of contact lenses for the required period of time prior to the screening refraction:

∙ Contact Lens Type Minimum Discontinuation Time Soft 1 Week Soft Extended Wear 2 Weeks Soft Toric 3 Weeks Rigid gas permeable 2 Weeks per decade of wear

• Signed written informed consent

• Willingness and ability to comply with schedule for follow-up visits