Investigating the Safety and Efficacy of the 1927-nm Thulium Laser for Soft Tissue Coagulation in Keratosis Pilaris

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Keratosis pilaris (KP) is a very common skin condition that affects up to 80% of adolescents and 40% of adults. Clinically, KP causes rough dry patches and tiny spiny bumps around the hair follicles, as well as redness and pigmentation changes, most often on the upper arms, thighs, cheeks, or buttocks. While KP is benign, it can be cosmetically very bothersome. Currently, treatment options for KP are limited, and consist of topical moisturizers and keratolytic agents, but often leads to suboptimal improvements. In literature, many laser treatment modalities for KP have been studied, with varying results. The primary aim of this pilot study is to investigate how KP, a predominantly follicular disorder, responds to treatment with the 1927-nm Thulium laser.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: t
View:

• Female or male, in good health, ages 18-65

• Voluntarily signed informed consent form

• Any Fitzpatrick skin type (I-VI)

• Clinically diagnosed keratosis pilaris of bilateral upper arms

• Willing to have photographs taken and agree to the use of photographs for regulatory, presentation, or marketing purposes

• Willing and able to follow protocol procedures and requirements

Locations
United States
Maryland
Johns Hopkins University
RECRUITING
Baltimore
Contact Information
Primary
Youkyung S Roh, MD
yroh2@jhmi.edu
410-502-7546
Backup
Ruizhi Wang
rwang@jhmi.edu
410-502-7546
Time Frame
Start Date: 2025-11
Estimated Completion Date: 2026-12
Participants
Target number of participants: 25
Treatments
Active_comparator: 1927-nm Thulium Laser therapy (right arm)
Participants will receive treatment for Keratosis Pilaris with the 1927-nm Thulium laser on the right arm.
Active_comparator: 1927-nm Thulium Laser therapy (left arm)
Participants will receive treatment for Keratosis Pilaris with the 1927-nm Thulium laser on the left arm.
Related Therapeutic Areas
Sponsors
Leads: Johns Hopkins University

This content was sourced from clinicaltrials.gov

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