Comparison Between Therapeutic Efficacy of Itraconazole Pulse Therapy and Terbinafine Therapy in Treatment of Tinea Capitis in Pediatric Population.
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Several studies globally have assessed the efficacy of terbinafine and itraconazole in the treatment of tinea capitis, but local data in this regard is scarce. Therefore, this study was planned with the aim of assessing the difference between the therapeutic efficacy of itraconazole pulse therapy and terbinafine in children with tinea capitis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 1
Maximum Age: 13
Healthy Volunteers: f
View:
• Any gender
• Aged 1-13 years
• With KOH mount positive before start of treatment
• Duration of disease more than 1 month
Locations
Other Locations
Pakistan
Jinnah Hospital/Allama Iqbal Medical College
RECRUITING
Lahore
Contact Information
Primary
Saima Aslam
samia_aslam30@hotmail.com
+923316210971
Backup
Fahad Iqbal, FCPS
fahad.iqbal141@gamil.com
+923346183034
Time Frame
Start Date: 2025-04-01
Estimated Completion Date: 2025-08-31
Participants
Target number of participants: 164
Treatments
Experimental: Terbinafine group
Patients will be given terbinafine in a dose of 62.5 mg for less than 20 kg body weight, 125 mg from 20 to 40 kg, and 250 mg for more than 40 kg for a period of 4 weeks.
Experimental: Itraconazole group
Patients will receive itraconazole a dose of 5 mg/kg/day for 7 days and then 14 days off. Three such pulses will be given to the patients of this group.
Related Therapeutic Areas
Sponsors
Leads: Muhammad Aamir Latif