Assessing the Role of Proton Pump Inhibitors in Reducing Aspiration Incidence in Pediatric Laryngomalacia Cases
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement, Behavioral, Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Laryngomalacia is the most common congenital laryngeal anomaly in children and is frequently associated with aspiration. This randomized controlled study aims to assess the role of proton pump inhibitor (PPI) therapy in reducing the incidence of aspiration in pediatric patients with laryngomalacia. Eligible participants will be randomly assigned to either a PPI treatment group or a control group. Clinical and swallowing assessments will be performed to compare aspiration incidence and swallowing outcomes between the two groups
Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 5
Healthy Volunteers: f
View:
• Children diagnosed with laryngomalacia by laryngoscopic examination with a history of recurrent choking attacks or aspiration symptoms.
• Children aged from 6 months to 5 years.
Locations
Other Locations
Egypt
faculty of Medicine, Minia University
RECRUITING
Minya
Time Frame
Start Date: 2026-04-28
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 60
Treatments
Experimental: PPI group
Participants receive PPI therapy in addition to vitamin D supplementation and feeding instructions.
Active_comparator: standard group
Participants receive vitamin D supplementation and feeding instructions only.
Related Therapeutic Areas
Sponsors
Leads: Minia University