Latest Advances

  • Condition: Retinal Ganglion Cell (RGC) Injury in Optic Neuropathies
  • Journal: BioMed research international
  • Treatment Used: Cell Replacement Therapy, Neuroprotection, and Gene Therapy
  • Number of Patients: 0
  • Published —
This review summarized experimental treatments targeting Retinal ganglion cells over the last decade.
  • Condition: Leber Hereditary Optic Neuropathy
  • Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • Treatment Used: Gene Therapy
  • Number of Patients: 7
  • Published —
This study investigated whether multilocus mitochondral mutations affect the efficacy of using gene therapy to treat patients with Leber hereditary optic neuropathy.
  • Condition: Leber Hereditary Optic Neuropathy (LOHN)
  • Journal: JAMA ophthalmology
  • Treatment Used: Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene (rAAV2/2-ND4)
  • Number of Patients: 15
  • Published —
This study examined the association between immune response and intraocular inflammation after ocular gene therapy with recombinant adeno-associated virus 2 carrying the ND4 gene (rAAV2/2-ND4) in patients with Leber hereditary optic neuropathy (LOHN).
  • Condition: Leber's Hereditary Optic Neuropathy
  • Journal: Ophthalmic research
  • Treatment Used: Gene Therapy
  • Number of Patients: 9
  • Published —
The study researched the effects and safety of gene therapy for Leber's Hereditary Optic Neuropathy.
Showing 1-4 of 4