Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
Randomised clinical trial comparing oral miltefosine associated with pentoxifylline to intravenous liposomal amphotericin b for the treatment of cutaneous and mucosal leishmaniasis
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: f
View:
• Active confirmed cutaneous leishmaniasis ou mucosal leishmaniasis
• Use of highly effective contraceptive method and a negative serologic pregnancy test (beta - HCG), if female in fertile phase
• Agree and sing informed consent form
Locations
Other Locations
Brazil
Hospital Universitario de Brasilia
RECRUITING
Brasília
Contact Information
Primary
Raimunda Sampaio, PhD
rnrsampaio@hotmail.com
+556120285415
Backup
Sofia Martins, PhD
sofiasalesm@gmail.com
+556120285415
Time Frame
Start Date: 2022-06-22
Estimated Completion Date: 2026-06
Participants
Target number of participants: 100
Treatments
Experimental: Oral Miltefosine and Pentoxifylline for Cutaneous Leishmaniasis
Experimental: Oral Miltefosine and Pentoxifylline for Mucous Leishmaniasis
Active_comparator: Intravenous Liposomal Amphotericin B for Cutaneous Leishmaniasis
Active_comparator: Intravenous Liposomal Amphotericin B for Mucous Leishmaniasis
Related Therapeutic Areas
Sponsors
Leads: University of Brasilia