Social-cognitive Functioning: Validation of a New Neuropsychological Test and Prediction of Social Behavioural Disorders in Daily Life

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

It is now established that disturbances in social cognition are frequent in neurology and that they contribute to the development of social conduct disorders. Their assessment is therefore essential, particularly in order to propose early and adapted care. However, this assessment remains limited today. A new serious game-type test, REALSoCog, has been developed to address the shortcomings of current tools and to highlight disturbances in social behaviors. The latter are not always observed in consultation although they are often reported by caregivers. The objective of this research is therefore to validate the REALSoCog task in a pathological population (currently being standardized in the general population: CER-U, IRB N°: 00012020-115). The clinical interest of this task will be tested with a group of patients suffering from a neurodegenerative disease (Alzheimer's disease (AD), dementia with Lewy bodies (DCL), fronto-temporal lobar degeneration (FTD)) in order to assess its sensitivity and specificity in the detection of social-cognitive disturbances, and in particular in terms of social behaviors (detection of social behavioral disorders reported in daily life). The objective is also to document the socio-cognitive profiles in the mentioned diseases thanks to a more ecological test, and to better understand the links between socio-cognitive processes on the one hand, and individual characteristics on the other hand (e.g. mood and social participation).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 90
Healthy Volunteers: t
View:

⁃ For patients:

• Patient aged between 18 and 90 years

• Mini Mental State Examination (MMSE) score greater than or equal to 20

• Patient able to express his or her non-opposition to participate in the study in an informed and autonomous manner

• Patient with a neurodegenerative pathology: FTD, AD or LBD.

⁃ For caregivers:

• Over 18 years of age

• Regular contact with the patient (≥ 2 times per month)

Locations
Other Locations
France
Hôpital de la Pitié-Salpêtrière
RECRUITING
Paris
Contact Information
Primary
Marc VERNY, Pr
marc.verny@aphp.fr
01 42 16 03 12
Backup
Pauline NARME
paulinenarme@gmail.com
06 08 98 38 04
Time Frame
Start Date: 2025-11-28
Estimated Completion Date: 2029-11-28
Participants
Target number of participants: 120
Treatments
Experimental: Patients
Patients suffering from a neurodegenerative disease (Alzheimer's disease (AD), dementia with Lewy bodies (DCL) or fronto-temporal lobar degeneration (FTD))
Other: Relatives
Caregivers or relatives of included patients, having regular contact with the patient (≥ 2 times per month).
Sponsors
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov