Nutrition-Optimized Prehabilitation's Impact on Perioperative Outcomes in Primary Hepatocellular Carcinoma: a Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The aim of this project is to investigate the effect of triple prehabilitation led by nutritional optimization in liver cancer patients' surgery. It improves the preoperative nutritional status of cancer patients, reduces the incidence of early postoperative complications, promotes postoperative recovery, and improves the quality of patients' survival. Patients were randomized into experimental and control groups based on exclusion and inclusion criteria. Nutritional interventions and exercise and psychological interventions for patients. Interventions will continue for two weeks prior to surgery. Routine clinical blood tests will be performed at the time of enrollment, on the first day before surgery and on the first, third and fifth days after surgery. Enrolled patients were followed up by telephone or outpatient clinic at 1,3,6 months postoperatively.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Patients diagnosed with primary liver cancer.

⁃ Patients between the ages of 18 and 70.

‣ Patients who are feasible for surgical treatment after clinical evaluation. ④Major organ function meets the following conditions: neutrophil count \>1.5\*109/L; platelet count \>100\* 109/L; hemoglobin \>90g/L; transaminase and creatinine \<twice the upper limit.

Locations
Other Locations
China
2nd Affiliated Hospital, School of Medicine, Zhejiang University, China
RECRUITING
Hangzhou
Contact Information
Primary
Yuan Ding
dingyuan@zju.edu.cn
+86 18858101960
Time Frame
Start Date: 2024-09-01
Estimated Completion Date: 2026-01-31
Participants
Target number of participants: 200
Treatments
Experimental: Nutritional optimization-led triple prehabilitation Intervention
Nutritional optimization-led triple prehabilitation
Other: Conventional triple prehabilitation Intervention
Conventional triple prehabilitation
Related Therapeutic Areas
Sponsors
Leads: Second Affiliated Hospital, School of Medicine, Zhejiang University

This content was sourced from clinicaltrials.gov

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