Multiparametric MRI for Optimized Imaging-based Characterization and Therapy Management of Hepatocellular Carcinoma

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This prospective observational study investigates using multiparametric magnetic resonance imaging (MRI) to improve the characterization and management of therapy for hepatocellular carcinoma (HCC). The goal is to evaluate whether advanced MRI parameters can support noninvasive diagnostic assessments and personalized treatment plans for patients with HCC. The study is being conducted at a single university center in Germany and includes adult patients with confirmed or suspected HCC. Participants will undergo standardized multiparametric MRI examinations, and the imaging data will be correlated with clinical, pathological, and therapeutic outcomes. No study-specific interventions or medications will be administered.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age ≥18 years

• Confirmed or suspected diagnosis of HCC

• Scheduled to receive TACE or SIRT as part of standard clinical care

• Eligibility for liver MRI

• Willing and able to provide written informed consent

Locations
Other Locations
Germany
Clinic of Radiology, University of Münster
RECRUITING
Münster
Contact Information
Primary
Max Masthoff, MD
max.masthoff@ukmuenster.de
+492518343018
Backup
Philipp Schindler, MD
philipp.schindler@ukmuenster.de
+492518343015
Time Frame
Start Date: 2025-05-01
Estimated Completion Date: 2028-05-01
Participants
Target number of participants: 128
Treatments
HCC patients undergoing TACE or SIRT
Patients with hepatocellular carcinoma scheduled for TACE or SIRT, undergoing multiparametric MRI at three defined time points.
Related Therapeutic Areas
Sponsors
Leads: University Hospital Muenster

This content was sourced from clinicaltrials.gov