Evaluation of Minimal Hepatic Encephalopathy in Patients With Cirrhosis and Portal Hypertension

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Minimal hepatic encephalopathy (MHE) is a subclinical cognitive impairment and represents the mildest type of hepatic encephalopathy (HE). Portal hypertension is the main complication of cirrhosis and is responsible of severe complications such as HE. The consequence of portal hypertension is the formation of the spontaneous portosystemic shunts (SPSS). The relationship between the SPSS and their characteristics and the prevalence of MHE in patient with cirrhosis is poorly known. The main objective of this study is to evaluate the MHE in patients with cirrhosis and portal hypertension.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patient with cirrhosis and portal hypertension older than 18 old

• Patient who underwent a CT scan or MRI in the last 3 months

• The Mini-Mental State (MMS) test \>25.

• Patient capable of receiving and understanding information relating to the study and of giving his written informed consent.

• Patient affiliated to the French social security system

Locations
Other Locations
France
Service d'Hépato-Gastroentérologie, Hôpitaux Civils
NOT_YET_RECRUITING
Colmar
Service d'Hépato-gastroentérologie, NHC
RECRUITING
Strasbourg
Contact Information
Primary
Armelle TAKEDA, PhD
armelle.takeda@ihu-strasbourg.eu
+33 390413608
Time Frame
Start Date: 2021-03-26
Estimated Completion Date: 2025-03-25
Participants
Target number of participants: 100
Treatments
Experimental: Patients with compensated cirrhosis and portal hypertension
Sponsors
Leads: IHU Strasbourg

This content was sourced from clinicaltrials.gov