Individual Nutrition Support in HBV-ACLF Patients at Nutrition Risk: a Randomized Controlled Trail
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to investigate the safety and efficacy of individual nutrition support for treating hepatitis b virus(HBV) related acute-on-chronic liver failure patients at nutrition risk
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 60
Healthy Volunteers: f
View:
• Age from 20 to 60 years old;
• Clinical diagnosis of chronic hepatitis b virus infection(positive hepatitis b surface antigen or positive hepatitis b virus DNA \>0.5 year
• serum total bilirubin level ≥12 mg/dl
• prothrombin time international ratio ≥1.5
• NRS≥ 3points
• COSSH-ACLF IIs \<8.4 points
Locations
Other Locations
China
Third Affiliated Hospital of Sun Yat-sen University
RECRUITING
Guangzhou
Contact Information
Primary
Li Zhipeng
lzp1219@126.com
+8613725480127
Backup
Peng Liang
pzp33@hotmail.com
+8613533978874
Time Frame
Start Date: 2023-11-23
Estimated Completion Date: 2024-10-31
Participants
Target number of participants: 60
Treatments
Experimental: Trail Group
30 patients will receive dietary counseling and individual nutrition support treatment based on Oral nutrition supplements and supplemented by parenteral nutrition.
No_intervention: Control Group
30 patients will receive standard care food provided by the hospital kitchen according to their ability and desire, standard care food provided by the hospital kitchen.
Related Therapeutic Areas
Sponsors
Leads: Third Affiliated Hospital, Sun Yat-Sen University