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Prospective Study Evaluating the Hemodynamic Impact of PAracetamol Administration in Patients Hospitalized in the REAnimation Intensive Care Unit

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Paracetamol is commonly used in case of pain or fever. Few previously clinical studies has highlighted an arterial hypotension linked to intravenous administration of paracetamol. Currently, fewer data are available on the link of intravenous administration of paracetamol and effects on arterial tension. The aim of this study is to describe the frequency of occurrence of significative arterial hypotension within one hour following intravenous or per os administration of paracetamol . Other factors who can be associated to occurence of significative arterial hypotension will be also observe (for example age, weight, pain, vasopressor dosage or sedative...)

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

⁃ Inclusion:

• 18 years of age or older

• Patient with arterial catheter

• Indication of paracetamol's administration by the patient's attending practitioner.

• No opposition to patient or support person participation in the study if the patient is unable to participate

Locations
Other Locations
France
CHU de NICE ARCHET
RECRUITING
Nice
Contact Information
Primary
Kamila BURDZENIDZE, Study nurse
crc@chu-nice.fr
04 92 03 92 20
Time Frame
Start Date: 2025-02-03
Estimated Completion Date: 2028-09
Participants
Target number of participants: 200
Treatments
Experimental: Treatment with paracetamol
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Universitaire de Nice

This content was sourced from clinicaltrials.gov