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Nociception Assessment During Rapid Sequence Induction: A Prospective Observational Study of Practices and Complications - The NARSI Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception using the Analgesia Nociception Index (ANI) during this procedure. This monocentric prospective observational study aims to describe the impact of RSI on pain measured by ANI, and to explore early complications (desaturation, hypotension, regurgitation) and factors associated with pain and complications. 150 patients undergoing RSI in the visceral surgery operating room at CHPG Monaco will be analyzed.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \>= 18 years

• Patient requiring tracheal intubation after rapid sequence induction in the visceral surgery operating room

• Pain monitoring by Analgesia Nociception Index (ANI) as part of general anesthesia

Locations
Other Locations
Monaco
Centre Hospitalier Princesse Grace
RECRUITING
Monaco
Contact Information
Primary
Remy WIDEHEM
remy.widehem@chpg.mc
+377 97 98 99 00
Backup
Celine DUGOURD
recherche.clinique@chpg.mc
+377 97 98 84 29
Time Frame
Start Date: 2026-05-21
Estimated Completion Date: 2028-05
Participants
Target number of participants: 150
Related Therapeutic Areas
Sponsors
Leads: Centre Hospitalier Princesse Grace

This content was sourced from clinicaltrials.gov