Intermittent Ephedrine Boluses for Prophylaxis Against Postinduction Hypotension in High-risk Patients Undergoing Major Abdominal Surgery: a Randomized Double-blinded Controlled Trial: a Randomized Double-blinded Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this work is to assess the efficacy of intermittent ephedrine boluses in prophylaxis against postinduction hypotension in high-risk patients undergoing major abdominal surgery, compared to standard care.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: f
View:
• Adult patients aged \>50 years,
• weight \>50 kg,
• American Society of Anesthesiologists (ASA) Physical Status score of \> I,
• undergoing major abdominal surgery
Locations
Other Locations
Egypt
Kasr Alainy Hospital
RECRUITING
Cairo
Contact Information
Primary
Maha Mostafa, MD
maha.mostafa@cu.edu.eg
+201000365115
Time Frame
Start Date: 2026-08-04
Estimated Completion Date: 2026-12
Participants
Target number of participants: 124
Treatments
Placebo_comparator: control
Normal Saline boluses
Active_comparator: ephedrine
ephedrine boluses
Related Therapeutic Areas
Sponsors
Leads: Cairo University