A Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination With Pembrolizumab Versus Pembrolizumab in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation
Who is this study for? Patients with advanced non-small cell lung cancer with KRAS G12C mutation
What treatments are being studied? MRTX849+Pembrolizumab
Status: Recruiting
Location: See all (733) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
The Phase 2 portion of this study evaluates the efficacy and safety of MRTX849 monotherapy and in combination with pembrolizumab in cohorts of patients with advanced NSCLC with KRAS G12C mutation and any PD-L1 TPS and who are candidates for first-line treatment. The Phase 3 portion of the study compares the efficacy of adagrasib in combination with pembrolizumab versus pembrolizumab in patients with unresectable, locally advanced or metastatic squamous or nonsquamous NSCLC with KRAS G12C mutation and PD-L1 TPS \>=50% and who are candidates for first line treatment.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Phase 2: Histologically confirmed diagnosis of unresectable or metastatic NSCLC with KRAS G12C mutation and any PD-L1 TPS
• Phase 3: Histologically confirmed diagnosis of unresectable or metastatic squamous or nonsquamous NSCLC with KRAS G12C mutation and PD-L1 TPS \>=50%
• Phase 3: Presence of evaluable or measurable disease per RECIST
• Phase 3: CNS Inclusion - Based on screening brain imaging, patients must have one of the following:
‣ No evidence of brain metastases
⁃ Untreated brain metastases not needing immediate local therapy
⁃ Previously treated brain metastases not needing immediate local therapy
Locations
United States
Arkansas
Highlands Oncology Group - Springdale
RECRUITING
Springdale
Arizona
Local Institution - 007-556-A
NOT_YET_RECRUITING
Goodyear
USOR - Arizona Oncology - Prescott Valley
RECRUITING
Prescott Valley
Local Institution - 007-568-A
NOT_YET_RECRUITING
Safford
Local Institution - 007-568-B
NOT_YET_RECRUITING
Safford
Local Institution - 007-568-C
NOT_YET_RECRUITING
Safford
Local Institution - 007-568-D
NOT_YET_RECRUITING
Safford
Local Institution - 007-568-E
NOT_YET_RECRUITING
Safford
Arizona Clinical Research Center
RECRUITING
Tucson
California
Providence - Saint Joseph Home Health - Anaheim
RECRUITING
Anaheim
The Oncology Institute of Hope and Innovation - Corporate Office
RECRUITING
Cerritos
Local Institution - 007-777
NOT_YET_RECRUITING
Fountain Valley
Local Institution - 007-778
NOT_YET_RECRUITING
Laguna Hills
Local Institution - 007-898-B
NOT_YET_RECRUITING
Long Beach
MemorialCare - Long Beach Medical Center
RECRUITING
Long Beach
TRIO - Cancer & Blood Specialty Clinic - Los Alamitos
RECRUITING
Los Alamitos
Local Institution - 007-579
WITHDRAWN
Los Angeles
Local Institution - Unk045
ACTIVE_NOT_RECRUITING
Rancho Mirage
San Francisco Veterans Affairs Medical Center
RECRUITING
San Francisco
UCSF Helen Diller Family Comprehensive Cancer Center
RECRUITING
San Francisco
Local Institution - 007-898-C
NOT_YET_RECRUITING
Santa Ana
Providence Medical Group - Santa Rosa
RECRUITING
Santa Rosa
Stockton Hematology Oncology Medical Group (SHOMG) - Stockton (Suite B)
RECRUITING
Stockton
Local Institution - 007-898-A
NOT_YET_RECRUITING
Whittier
Colorado
Local Institution - 007-872-H
NOT_YET_RECRUITING
Aurora
Local Institution - 007-872-D
NOT_YET_RECRUITING
Boulder
Local Institution - 007-872-L
NOT_YET_RECRUITING
Centennial
Local Institution - 007-872-C
NOT_YET_RECRUITING
Colorado Springs
Local Institution - 007-872-K
NOT_YET_RECRUITING
Colorado Springs
Local Institution - 007-872-E
NOT_YET_RECRUITING
Denver
Local Institution - 007-872-I
NOT_YET_RECRUITING
Denver
Local Institution - 007-872-A
NOT_YET_RECRUITING
Lakewood
Local Institution - 007-872-J
NOT_YET_RECRUITING
Littleton
USOR - Rocky Mountain Cancer Centers - Lone Tree
RECRUITING
Lone Tree
Local Institution - 007-872-G
NOT_YET_RECRUITING
Longmont
Local Institution - 007-872-B
NOT_YET_RECRUITING
Pueblo
Local Institution - 007-872-F
NOT_YET_RECRUITING
Thornton
Connecticut
Eastern Connecticut Hematology and Oncology Associates
RECRUITING
Norwich
Washington, D.c.
Local Institution - 007-5476
NOT_YET_RECRUITING
Washington D.c.
Florida
GenesisCare USA
RECRUITING
Aventura
Bay Pines Veterans Affairs Healthcare System
RECRUITING
Bay Pines
Local Institution - 007-922-A
NOT_YET_RECRUITING
Bonita Springs
Local Institution - 007-922-D
NOT_YET_RECRUITING
Bradenton
Local Institution - 007-922-E
NOT_YET_RECRUITING
Cape Coral
Local Institution - 007-896-A
NOT_YET_RECRUITING
Celebration
Local Institution - 007-926-B
NOT_YET_RECRUITING
Daytona Beach
Local Institution - 007-562-B
NOT_YET_RECRUITING
Fleming Island
Local Institution - 007-922-B
NOT_YET_RECRUITING
Fort Myers
Local Institution - 007-922-C
NOT_YET_RECRUITING
Fort Myers
SCRI - Florida Cancer Specialists - South Region Research Office
RECRUITING
Fort Myers
21st Century Oncology of Jacksonville - North Lee Street
RECRUITING
Jacksonville
Cancer Specialists of North Florida - Southpoint
RECRUITING
Jacksonville
Local Institution - 007-562-C
NOT_YET_RECRUITING
Jacksonville
Local Institution - 007-562-D
NOT_YET_RECRUITING
Jacksonville
Local Institution - 007-562-E
NOT_YET_RECRUITING
Jacksonville
Local Institution - 007-562-G
NOT_YET_RECRUITING
Jacksonville
Local Institution - 007-829
WITHDRAWN
Jacksonville
Local Institution - 007-562-F
NOT_YET_RECRUITING
Jacksonville Beach
Miami Veterans Affairs Healthcare System
RECRUITING
Miami
Local Institution - 007-922-F
NOT_YET_RECRUITING
Naples
Local Institution - 007-922-G
NOT_YET_RECRUITING
Naples
AdventHealth Orlando
RECRUITING
Orlando
USOR - Woodlands Medical Specialists
RECRUITING
Pensacola
Local Institution - 007-922-H
NOT_YET_RECRUITING
Port Charlotte
Local Institution - 007-562-A
NOT_YET_RECRUITING
Saint Augustine
Local Institution - 007-922-I
NOT_YET_RECRUITING
Sarasota
Local Institution - 007-922-J
NOT_YET_RECRUITING
Sarasota
Local Institution - 007-926-D
NOT_YET_RECRUITING
Stuart
Local Institution - 007-924-A
NOT_YET_RECRUITING
Tallahassee
SCRI - Florida Cancer Specialists - Tallahassee Cancer Center
RECRUITING
Tallahassee
James A. Haley Veterans Hospital
RECRUITING
Tampa
Local Institution - Unk065
ACTIVE_NOT_RECRUITING
Tampa
Local Institution - 007-922-K
NOT_YET_RECRUITING
Venice
Local Institution - 007-922-L
NOT_YET_RECRUITING
Venice
Local Institution - 007-926-C
NOT_YET_RECRUITING
Vero Beach
Local Institution - 007-926-A
NOT_YET_RECRUITING
Wellington
SCRI - Florida Cancer Specialists - West Palm Beach
RECRUITING
West Palm Beach
Local Institution - Unk072
ACTIVE_NOT_RECRUITING
Weston
Georgia
University Cancer & Blood Center (UCBC) - Athens
RECRUITING
Athens
Local Institution - Unk052
ACTIVE_NOT_RECRUITING
Atlanta
Local Institution - 007-786-C
NOT_YET_RECRUITING
Carrollton
Local Institution - 007-786-A
NOT_YET_RECRUITING
Cartersville
Local Institution - 007-786-D
NOT_YET_RECRUITING
Douglasville
Local Institution - 007-786-B
NOT_YET_RECRUITING
Hiram
Central Georgia Cancer Care - Macon
RECRUITING
Macon
Northwest Georgia Oncology Centers Wellstar - Marietta
RECRUITING
Marietta
Hawaii
Local Institution - 007-897
WITHDRAWN
Honolulu
Local Institution - Unk005
ACTIVE_NOT_RECRUITING
Honolulu
Illinois
Local Institution - 007-883-A
NOT_YET_RECRUITING
Arlington Heights
Local Institution - 007-955
WITHDRAWN
Chicago
University of Chicago
RECRUITING
Chicago
Loyola University Medical Center
RECRUITING
Maywood
USOR - Illinois Cancer Specialists - Niles
RECRUITING
Niles
Advocate Medical Group Oncology
RECRUITING
Park Ridge
Local Institution - Unk061
ACTIVE_NOT_RECRUITING
Peoria
Indiana
Goshen Center for Cancer Care
RECRUITING
Goshen
Kansas
Local Institution - 007-942-B
NOT_YET_RECRUITING
Chanute
Local Institution - 007-942-D
NOT_YET_RECRUITING
El Dorado
Local Institution - 007-942-E
NOT_YET_RECRUITING
Independence
Local Institution - 007-942-F
NOT_YET_RECRUITING
Kingman
Local Institution - 007-942-G
NOT_YET_RECRUITING
Liberal
Local Institution - 007-942-H
NOT_YET_RECRUITING
Mcpherson
MidAmerica Cancer Care - Research
RECRUITING
Merriam
Local Institution - 007-942-I
NOT_YET_RECRUITING
Newton
Local Institution - 007-942-J
NOT_YET_RECRUITING
Parsons
Local Institution - 007-942-K
NOT_YET_RECRUITING
Pratt
Local Institution - 007-942-L
NOT_YET_RECRUITING
Salina
Local Institution - 007-942-M
NOT_YET_RECRUITING
Wellington
Local Institution - Unk032
ACTIVE_NOT_RECRUITING
Westwood
Cancer Center of Kansas - Wichita - Heritage Plaza
RECRUITING
Wichita
Local Institution - 007-942-A
NOT_YET_RECRUITING
Wichita
Local Institution - 007-942-N
NOT_YET_RECRUITING
Winfield
Kentucky
Lexington Medical Cancer Center Hematology/Oncology
RECRUITING
Lexington
Local Institution - 007-388-A
NOT_YET_RECRUITING
Louisville
University of Louisville
RECRUITING
Louisville
Louisiana
Local Institution - Unk011
ACTIVE_NOT_RECRUITING
Baton Rouge
Local Institution - 007-994-A
NOT_YET_RECRUITING
Covington
Pontchartrain Cancer Center - Covington Office
RECRUITING
Covington
Massachusetts
Dana-Farber Cancer Institute
RECRUITING
Boston
Dana-Farber Cancer Institute at St. Elizabeths Medical Center
RECRUITING
Brighton
Brigham and Womens/Mass General Health Care Center at Foxborough
RECRUITING
Foxborough
Dana-Farber Cancer Institute - Merrimack Valley
RECRUITING
Methuen
Dana-Farber Brigham and Womens Cancer Center at Milford Regional
RECRUITING
Milford
Dana-Farber Brigham Cancer Center at South Shore Health
RECRUITING
South Weymouth
Maryland
The Sidney Kimmel Comprehensive Cancer Center
RECRUITING
Baltimore
Minnesota
USOR - Minnesota Oncology - Burnsville
RECRUITING
Burnsville
Local Institution - 007-589A
NOT_YET_RECRUITING
Edina
Local Institution - 007-822
WITHDRAWN
Minneapolis
Local Institution - Unk006
ACTIVE_NOT_RECRUITING
Minneapolis
Local Institution - 007-830
WITHDRAWN
Rochester
Mississippi
Jackson Oncology Associates - The Hederman Cancer Center
RECRUITING
Jackson
North Carolina
Duke University Medical Center
RECRUITING
Durham
Nebraska
Local Institution - 007-590D
NOT_YET_RECRUITING
Grand Island
Local Institution - 007-590A
NOT_YET_RECRUITING
Omaha
Local Institution - 007-590B
NOT_YET_RECRUITING
Omaha
Nebraska Cancer Specialists - Midwest Cancer Center - Legacy
RECRUITING
Omaha
Local Institution - 007-590C
NOT_YET_RECRUITING
Papillion
New Jersey
Local Institution - 007-993
WITHDRAWN
Belleville
Astera Cancer Care - East Brunswick
RECRUITING
East Brunswick
John Theurer Cancer Center
RECRUITING
Hackensack
Local Institution - 007-975-A
NOT_YET_RECRUITING
Somerset
Local Institution - 007-975-B
NOT_YET_RECRUITING
Somerset
Local Institution - 007-975-C
NOT_YET_RECRUITING
Somerset
Local Institution - 007-975-D
NOT_YET_RECRUITING
Somerset
Holy Name Medical Center
RECRUITING
Teaneck
Nevada
Local Institution - 007-938A
NOT_YET_RECRUITING
Las Vegas
Local Institution - 007-938B
NOT_YET_RECRUITING
Las Vegas
OptumCare Nevada
RECRUITING
Las Vegas
New York
New York Oncology Hematology - Albany Medical Center
RECRUITING
Albany
Local Institution - Unk077
ACTIVE_NOT_RECRUITING
Rhinebeck
Montefiore Medical Center
RECRUITING
The Bronx
Ohio
Local Institution - 007-893-B
NOT_YET_RECRUITING
Cincinnati
Local Institution - 007-893-C
NOT_YET_RECRUITING
Cincinnati
USOR - Oncology Hematology Care - Blue Ash
RECRUITING
Cincinnati
University Hospitals Cleveland Medical Center
RECRUITING
Cleveland
Mark H. Zangmeister Cancer Center
RECRUITING
Columbus
Local Institution - 007-893-A
NOT_YET_RECRUITING
Fairfield
Kettering Health Cancer Center - Main Campus
RECRUITING
Kettering
Tricounty Hematology and Oncology - Massillon
RECRUITING
Massillon
Oregon
USOR - Willamette Valley Cancer Institute and Research Center - Eugene
RECRUITING
Eugene
Local Institution - 007-885A
NOT_YET_RECRUITING
Portland
Local Institution - 007-885B
NOT_YET_RECRUITING
Portland
Oregon Oncology Specialists
RECRUITING
Salem
Local Institution - 007-885C
NOT_YET_RECRUITING
Tigard
Pennsylvania
Local Institution - Unk041
ACTIVE_NOT_RECRUITING
Allentown
Veterans Affairs Pittsburgh Healthcare System - University Drive Campus
RECRUITING
Pittsburgh
Rhode Island
Local Institution - 007-960
WITHDRAWN
Providence
South Carolina
Local Institution - Unk038
ACTIVE_NOT_RECRUITING
Charleston
Local Institution - 007-5475
WITHDRAWN
Spartanburg
South Dakota
Avera Cancer Institute
RECRUITING
Sioux Falls
Tennessee
Local Institution - 007-928-L
NOT_YET_RECRUITING
Dickson
Local Institution - 007-928-J
NOT_YET_RECRUITING
Franklin
Local Institution - 007-928-G
NOT_YET_RECRUITING
Gallatin
West Cancer Center & Research Institute - East Campus
RECRUITING
Germantown
Local Institution - 007-928-A
NOT_YET_RECRUITING
Hendersonville
Local Institution - 007-928-D
NOT_YET_RECRUITING
Hermitage
Local Institution - 007-928-H
NOT_YET_RECRUITING
Lebanon
Local Institution - 007-928-F
NOT_YET_RECRUITING
Murfreesboro
Local Institution - 007-928-B
NOT_YET_RECRUITING
Nashville
Local Institution - 007-928-C
NOT_YET_RECRUITING
Nashville
Local Institution - 007-928-E
NOT_YET_RECRUITING
Nashville
Local Institution - 007-928-K
NOT_YET_RECRUITING
Nashville
Tennessee Oncology - Nashville - Centennial Clinic - Medical Oncology
RECRUITING
Nashville
Local Institution - 007-928-M
NOT_YET_RECRUITING
Shelbyville
Local Institution - 007-928-I
NOT_YET_RECRUITING
Smyrna
Texas
Local Institution - 007-554B
NOT_YET_RECRUITING
Abilene
Local Institution - 007-554G
NOT_YET_RECRUITING
Amarillo
Local Institution - 007-879-A
NOT_YET_RECRUITING
Arlington
Local Institution - 007-879-B
NOT_YET_RECRUITING
Arlington
Local Institution - 007-892-A
NOT_YET_RECRUITING
Austin
Local Institution - 007-892-B
NOT_YET_RECRUITING
Austin
USOR - Texas Oncology - Dallas Fort Worth (DFW) - South Austin
RECRUITING
Austin
Local Institution - 007-879-C
NOT_YET_RECRUITING
Bedford
Local Institution - 007-592
WITHDRAWN
Dallas
Local Institution - Unk059
ACTIVE_NOT_RECRUITING
Dallas
Texas Oncology - Dallas Fort Worth (DFW) - Baylor Charles A. Sammons Cancer Center
RECRUITING
Dallas
USOR - Texas Oncology Northeast Texas - Denison
RECRUITING
Denison
Local Institution - 007-554C
NOT_YET_RECRUITING
El Paso
Local Institution - 007-554E
NOT_YET_RECRUITING
El Paso
Local Institution - 007-554F
NOT_YET_RECRUITING
El Paso
USOR - Texas Oncology - Fredericksburg
RECRUITING
Fredericksburg
Local Institution - 007-848
ACTIVE_NOT_RECRUITING
Houston
Local Institution - 007-999
NOT_YET_RECRUITING
Irving
Local Institution - 007-890-B
NOT_YET_RECRUITING
Longview
Local Institution - 007-554A
NOT_YET_RECRUITING
Midland
USOR - Texas Oncology - Dallas Fort Worth (DFW) - Odessa West Texas Cancer Center
RECRUITING
Odessa
USOR - Texas Oncology - The Woodlands
RECRUITING
The Woodlands
Local Institution - 007-890-A
NOT_YET_RECRUITING
Tyler
Local Institution - 007-554D
NOT_YET_RECRUITING
Wichita Falls
Utah
Local Institution - 007-912
WITHDRAWN
Salt Lake City
Virginia
Local Institution - 007-814-A
NOT_YET_RECRUITING
Alexandria
Local Institution - 007-814-D
NOT_YET_RECRUITING
Arlington
USOR - Virginia Cancer Specialists - Fairfax Office
RECRUITING
Fairfax
Local Institution - 007-814-B
NOT_YET_RECRUITING
Gainesville
Local Institution - 007-814-C
NOT_YET_RECRUITING
Leesburg
Virginia Cancer Institute - West End
RECRUITING
Richmond
Washington
USOR - Northwest Cancer Specialists, P.C. dba Compass Oncology - Vancouver Cancer Center
RECRUITING
Vancouver
Wisconsin
Local Institution - Unk057
ACTIVE_NOT_RECRUITING
Madison
Local Institution - Unk068
ACTIVE_NOT_RECRUITING
Madison
West Virginia
Local Institution - Unk064
ACTIVE_NOT_RECRUITING
Huntington
Other Locations
Argentina
Local Institution - 007-5001
NOT_YET_RECRUITING
Belgrano
Local Institution - Unk053
ACTIVE_NOT_RECRUITING
Buenos Aires
Local Institution - 007-435
NOT_YET_RECRUITING
Ciudad Autonoma De Buenos Aires
Local Institution - Unk043
ACTIVE_NOT_RECRUITING
Ciudad Autonoma De Buenos Aires
Local Institution - Unk033
ACTIVE_NOT_RECRUITING
Porto Alegre
Local Institution - Unk020
ACTIVE_NOT_RECRUITING
Río Cuarto
Local Institution - 007-5004
NOT_YET_RECRUITING
Rosario
Local Institution - 007-5003
NOT_YET_RECRUITING
San Pedro
Australia
Ballarat Regional Integrated Cancer Center
RECRUITING
Ballarat
Flinders Medical Centre
RECRUITING
Bedford Park
Local Institution - 007-004
WITHDRAWN
Clayton
Canberra Hospital
RECRUITING
Garran
Local Institution - 007-1003
NOT_YET_RECRUITING
Hyde Park
Local Institution - 007-1002
NOT_YET_RECRUITING
Port Macquarie
Cancer Care Wollongong
RECRUITING
Wollongong
Princess Alexandra Hospital
RECRUITING
Woolloongabba
Austria
Klinikum Klagenfurt Am Worthersee
RECRUITING
Klagenfurt
Universitatsklinikum Krems
RECRUITING
Krems
Ordensklinikum Linz Elisabethinen
RECRUITING
Linz
Wiener Gesundheitsverbund - Klinik Floridsdorf
RECRUITING
Vienna
Wiener Gesundheitsverbund - Klinik Hietzing
RECRUITING
Vienna
Belgium
Universitair Ziekenhuis Antwerpen
RECRUITING
Edegem
Algemeen Ziekenhuis Maria Middelares
RECRUITING
Ghent
Jessa Ziekenhuis - Campus Virga Jesse
RECRUITING
Hasselt
Local Institution - 007-152
WITHDRAWN
Roeselare
Brazil
Local Institution - 007-457
NOT_YET_RECRUITING
Barretos
Local Institution - Unk060
ACTIVE_NOT_RECRUITING
Barretos
Local Institution - Unk002
ACTIVE_NOT_RECRUITING
Ijuí
Local Institution - Unk050
ACTIVE_NOT_RECRUITING
Lajeado
Local Institution - 007-458
NOT_YET_RECRUITING
Natal
Local Institution - 007-459
NOT_YET_RECRUITING
Porto Alegre
Local Institution - Unk015
ACTIVE_NOT_RECRUITING
Porto Alegre
Local Institution - Unk003
ACTIVE_NOT_RECRUITING
Rio De Janeiro
Local Institution - Unk019
ACTIVE_NOT_RECRUITING
São José Do Rio Preto
Local Institution - Unk074
ACTIVE_NOT_RECRUITING
São Paulo
Bulgaria
Multiprofile Hospital For Active Treatment - Dr. Tota Venkova
RECRUITING
Gabrovo
Specialized Hospital for Active Oncology Treatment - Haskovo SLLC (SBALO - Haskovo - EOOD)
RECRUITING
Haskovo
Complex Oncology Center - Plovdiv - Base II
RECRUITING
Plovdiv
University Multiprofile Hospital for Active Treatment St. Ivan Rilski
RECRUITING
Sofia
Complex Oncology Center - Vratsa
RECRUITING
Vratsa
Canada
Cross Cancer Institute
RECRUITING
Edmonton
Local Institution - 007-489
WITHDRAWN
London
Local Institution - 007-490
ACTIVE_NOT_RECRUITING
Montreal
Ottawa Hospital - General Campus
RECRUITING
Ottawa
Princess Margaret Cancer Centre
RECRUITING
Toronto
British Columbia Cancer Agency - Vancouver
RECRUITING
Vancouver
Chile
Local Institution - Unk028
ACTIVE_NOT_RECRUITING
Santiago
Local Institution - Unk073
ACTIVE_NOT_RECRUITING
Temuco
China
Beijing Cancer hospital
RECRUITING
Beijing
Beijing Cancer Hospital/No.1 Thoracic Oncology Department
RECRUITING
Beijing
Beijing Cancer Hospital/Thoracic Oncology(2nd) Department
RECRUITING
Beijing
Cancer Hospital Chinese Academy of Medical Sciences/Medical Oncology Department
RECRUITING
Beijing
Local Institution - 007-027-Ph2
COMPLETED
Beijing
Local Institution - 007-038
WITHDRAWN
Beijing
Local Institution - 007-040
WITHDRAWN
Beijing
Local Institution - 007-040-Ph2
NOT_YET_RECRUITING
Beijing
Local Institution - 007-050
WITHDRAWN
Beijing
Local Institution - 007-707
WITHDRAWN
Beijing
Local Institution - 007-707-Ph2
ACTIVE_NOT_RECRUITING
Beijing
Local Institution - 1025
WITHDRAWN
Beijing
Local Institution - 1025-Ph2
NOT_YET_RECRUITING
Beijing
Local Institution - 007-051
WITHDRAWN
Bengbu
The First Affiliated Hospital of Bengbu Medical College/Department of Respiratory and Critical Care Medicine
RECRUITING
Bengbu
Local Institution - 007-717-Ph2
ACTIVE_NOT_RECRUITING
Changchun
Local Institution - 1006
WITHDRAWN
Changchun
Local Institution - 1006-Ph2
NOT_YET_RECRUITING
Changchun
The First Bethune Hospital Of Jilin University/Oncology Department
RECRUITING
Changchun
Hunan Cancer Hospital/Thoracic Medicine Department II
RECRUITING
Changsha
Local Institution - 007-701-Ph2
ACTIVE_NOT_RECRUITING
Changsha
Local Institution - 007-710
WITHDRAWN
Chengdu
Local Institution - 007-710-Ph2
COMPLETED
Chengdu
Local Institution - 007-720-Ph2
ACTIVE_NOT_RECRUITING
Chengdu
Sichuan Cancer hospital
RECRUITING
Chengdu
West China Hospital of Sichuan University
RECRUITING
Chengdu
Chongqing University Three Gorges Hospital/Respiratory Ward of Tumor Center
RECRUITING
Chongqing
Local Institution - 007-053
WITHDRAWN
Chongqing
Local Institution - 007-718-Ph3
NOT_YET_RECRUITING
Chongqing
Local Institution - 1029
WITHDRAWN
Chongqing
Local Institution - 1029-Ph2
NOT_YET_RECRUITING
Chongqing
Fujian Cancer Hospital
RECRUITING
Fuzhou
Fujian Cancer Hospital/Thoracic Oncology Department
RECRUITING
Fuzhou
Local Institution - 007-039
WITHDRAWN
Fuzhou
Local Institution - 1046
WITHDRAWN
Fuzhou
Local Institution - 1046-Ph2
NOT_YET_RECRUITING
Fuzhou
Local Institution - 007-705
WITHDRAWN
Guangzhou
Local Institution - 007-705-Ph2
ACTIVE_NOT_RECRUITING
Guangzhou
Local Institution - 007-712
WITHDRAWN
Guangzhou
Local Institution - 1022
WITHDRAWN
Guangzhou
Local Institution - 1022-Ph2
NOT_YET_RECRUITING
Guangzhou
Nanfang Hospital, Southern Medical University/Respiratory Medicine Department
RECRUITING
Guangzhou
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING
Guangzhou
The First Affiliated Hospital of Guangzhou Medical University/Oncology Department
RECRUITING
Guangzhou
Local Institution - 007-036
WITHDRAWN
Hangzhou
Local Institution - 007-036-Ph2
NOT_YET_RECRUITING
Hangzhou
Local Institution - 007-716
WITHDRAWN
Hangzhou
Local Institution - 007-716-Ph2
COMPLETED
Hangzhou
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITING
Hangzhou
Zhejiang Cancer Hospital
RECRUITING
Hangzhou
Zhejiang Cancer Hospital/Thoracic Medicine Department
RECRUITING
Hangzhou
Cancer Hospital affiliated to Harbin Medical University/Ward 3 of Respiratory Medicine Department
RECRUITING
Harbin
Local Institution - 007-028
WITHDRAWN
Harbin
Local Institution - 007-028-Ph2
COMPLETED
Harbin
Anhui Provincial Hospital
RECRUITING
Hefei
Local Institution - 007-026
WITHDRAWN
Hefei
Local Institution - 007-026-Ph2
ACTIVE_NOT_RECRUITING
Hefei
Local Institution - 007-739
WITHDRAWN
Hefei
Local Institution - 007-739-Ph2
NOT_YET_RECRUITING
Hefei
Local Institution - 007-747
WITHDRAWN
Hefei
Local Institution - 007-708-Ph2
ACTIVE_NOT_RECRUITING
Jinan
Shandong Cancer Hospital
RECRUITING
Jinan
Local Institution - 007-385
WITHDRAWN
Kunming
Local Institution - 007-385-Ph3
NOT_YET_RECRUITING
Kunming
Local Institution - 007-745
WITHDRAWN
Kunming
Local Institution - 007-745-Ph2
NOT_YET_RECRUITING
Kunming
Local Institution - 1032
WITHDRAWN
Kunming
Local Institution - 1032-Ph2
NOT_YET_RECRUITING
Kunming
Linyi Cancer Hospital/Oncology Department
RECRUITING
Linyi
Local Institution - 007-703
WITHDRAWN
Linyi
Local Institution - 007-703-Ph2
NOT_YET_RECRUITING
Linyi
Local Institution - 007-737-Ph2
NOT_YET_RECRUITING
Linyi
Local Institution - 007-704
WITHDRAWN
Liuzhou
Local Institution - 007-704-Ph2
NOT_YET_RECRUITING
Liuzhou
Local Institution - 007-711
WITHDRAWN
Luzhou
Local Institution - 007-711-Ph2
NOT_YET_RECRUITING
Luzhou
Local Institution - 1040
WITHDRAWN
Nanchang
Local Institution - 1040-Ph2
NOT_YET_RECRUITING
Nanchang
The First Affiliated Hospital of Nanchang University
RECRUITING
Nanchang
The First Affiliated Hospital of Nanchang University/Respiratory and Critical Care Medicine Department
RECRUITING
Nanchang
Local Institution - 1018
WITHDRAWN
Nanjing
Local Institution - 1018-Ph2
NOT_YET_RECRUITING
Nanjing
Local Institution - 1020
WITHDRAWN
Nanjing
Local Institution - 1020-Ph2
NOT_YET_RECRUITING
Nanjing
Local Institution - 1021
WITHDRAWN
Nanjing
Local Institution - 1021-Ph2
NOT_YET_RECRUITING
Nanjing
Nanjing First Hospital/Department of Respiratory and Critical Care Medicine
RECRUITING
Nanjing
Nanjing First Hospital/Respiratory Department
RECRUITING
Nanjing
Guangxi Medical University Cancer Hospital/Department of Respiratory Oncology
RECRUITING
Nanning
Local Institution - 007-384
WITHDRAWN
Nanning
Local Institution - 007-744-Ph2
NOT_YET_RECRUITING
Nanning
Local Institution - 1038
WITHDRAWN
Nanning
Local Institution - 1038-Ph2
NOT_YET_RECRUITING
Nanning
Local Institution - 1004
WITHDRAWN
Nantong
Local Institution - 1004-Ph2
NOT_YET_RECRUITING
Nantong
Local Institution - 1043
WITHDRAWN
Qingdao
Local Institution - 1043-Ph2
NOT_YET_RECRUITING
Qingdao
Fudan University Shanghai Cancer Center/Thoracic Oncology Department
RECRUITING
Shanghai
Local Institution - 007-024
WITHDRAWN
Shanghai
Local Institution - 007-024-Ph2
ACTIVE_NOT_RECRUITING
Shanghai
Local Institution - 007-024-Ph3
NOT_YET_RECRUITING
Shanghai
Local Institution - 007-035
WITHDRAWN
Shanghai
Local Institution - 007-035-Ph2
COMPLETED
Shanghai
Local Institution - 007-709
WITHDRAWN
Shanghai
Local Institution - 007-709-Ph2
ACTIVE_NOT_RECRUITING
Shanghai
Shanghai Chest Hospital-Oncology department
RECRUITING
Shanghai
Liaoning Cancer Hospital & Institute/The 2nd Chest Medical Department
RECRUITING
Shenyang
Local Institution - 007-702
WITHDRAWN
Shenyang
Local Institution - 007-741
WITHDRAWN
Shenyang
Local Institution - 007-741-Ph2
NOT_YET_RECRUITING
Shenyang
Local Institution - 007-749
WITHDRAWN
Shenyang
Local Institution - 1008
WITHDRAWN
Shenyang
Local Institution - 1008-Ph2
NOT_YET_RECRUITING
Shenyang
Shengjing Hospital of China Medical University
RECRUITING
Shenyang
Local Institution - 007-052
WITHDRAWN
Shenzhen
Shenzhen People's Hospital/Department of Respiratory and Critical Care Medicine
RECRUITING
Shenzhen
Local Institution - 007-742
WITHDRAWN
Shijiazhuang
The Fourth Hospital of Hebei Medical University
RECRUITING
Shijiazhuang
Local Institution - 007-740
WITHDRAWN
Taiyuan
Local Institution - 007-740-Ph2
NOT_YET_RECRUITING
Taiyuan
Local Institution - 007-748
WITHDRAWN
Taiyuan
Shanxi Provincial Cancer Hospital/Respiratory Medicine
RECRUITING
Taiyuan
Local Institution - 1050
WITHDRAWN
Taizhou
Local Institution - 1050-Ph2
NOT_YET_RECRUITING
Taizhou
Taizhou Hospital Of Zhejiang Province
RECRUITING
Taizhou
Local Institution - 007-743
WITHDRAWN
Ürümqi
Local Institution - 1036
WITHDRAWN
Ürümqi
Local Institution - 1036-Ph2
NOT_YET_RECRUITING
Ürümqi
Xinjiang Medical University Cancer Hospital - Urumqi
RECRUITING
Ürümqi
Local Institution - 007-700
WITHDRAWN
Wuhan
Local Institution - 007-700-Ph2
NOT_YET_RECRUITING
Wuhan
Local Institution - 007-719-Ph2
COMPLETED
Wuhan
Union Hospital Affiliated with Tongji Medical College of Huazhong University of Science and Technology/Cancer Center Department
RECRUITING
Wuhan
Local Institution - 007-718-Ph2
ACTIVE_NOT_RECRUITING
Xi'an
Local Institution - 007-721
WITHDRAWN
Xi'an
Local Institution - 007-721-Ph2
ACTIVE_NOT_RECRUITING
Xi'an
The First Affiliated Hospital of Xi'an Jiaotong University/Medical Oncology Department
RECRUITING
Xi'an
Local Institution - 007-714
WITHDRAWN
Xiamen
Local Institution - 007-714-Ph2
NOT_YET_RECRUITING
Xiamen
Local Institution - 007-732
WITHDRAWN
Xiamen
Local Institution - 007-732-Ph2
NOT_YET_RECRUITING
Xiamen
The First Affiliated Hospital of Xiamen University/Medical Oncology Department
RECRUITING
Xiamen
Local Institution - 1012-Ph2
NOT_YET_RECRUITING
Xinxiang
Local Institution - 1017
WITHDRAWN
Xuzhou
Local Institution - 1017-Ph2
NOT_YET_RECRUITING
Xuzhou
Local Institution - 007-746
WITHDRAWN
Yinchuan
Local Institution - 007-746-Ph3
NOT_YET_RECRUITING
Yinchuan
Local Institution - 007-021-Ph2
COMPLETED
Zhengzhou
Local Institution - 007-021-Ph3
NOT_YET_RECRUITING
Zhengzhou
Local Institution - 007-715
WITHDRAWN
Zhengzhou
Local Institution - 007-715-Ph2
NOT_YET_RECRUITING
Zhengzhou
Local Institution - 007-730-Ph2
NOT_YET_RECRUITING
Zhengzhou
Local Institution - 007-730-Ph3
NOT_YET_RECRUITING
Zhengzhou
Local Institution - 1010
WITHDRAWN
Zhengzhou
Local Institution - 1010-Ph2
NOT_YET_RECRUITING
Zhengzhou
Colombia
Local Institution - Unk021
ACTIVE_NOT_RECRUITING
Medellín
Local Institution - Unk027
ACTIVE_NOT_RECRUITING
Montería
Croatia
Local Institution - 007-4000
WITHDRAWN
Pula
Specijalna Bolnica Medico
RECRUITING
Rijeka
Local Institution - 007-4002
NOT_YET_RECRUITING
Zagreb
Denmark
Local Institution - 007-172
WITHDRAWN
Odense
Sjukhus Sonderjylland
RECRUITING
Sønderborg
Local Institution - 007-170
NOT_YET_RECRUITING
Vejle
Finland
Local Institution - 007-183
NOT_YET_RECRUITING
Helsinki
Local Institution - 007-182
NOT_YET_RECRUITING
Tampere
France
Local Institution - 007-689
NOT_YET_RECRUITING
Angers
Local Institution - 007-1992
NOT_YET_RECRUITING
Boulogne-billancourt
Local Institution - 007-194
NOT_YET_RECRUITING
Brest
Local Institution - 007-196
NOT_YET_RECRUITING
Caen
Local Institution - 007-190
NOT_YET_RECRUITING
Créteil
Local Institution - 007-683
NOT_YET_RECRUITING
La Tronche
Local Institution - 007-195
NOT_YET_RECRUITING
Limoges
Local Institution - 007-1993
NOT_YET_RECRUITING
Lorient
Local Institution - 007-199
NOT_YET_RECRUITING
Marseille
Local Institution - 007-687
NOT_YET_RECRUITING
Marseille
Local Institution - 007-200
NOT_YET_RECRUITING
Montpellier
Local Institution - 007-666
NOT_YET_RECRUITING
Mulhouse
Local Institution - 007-664
NOT_YET_RECRUITING
Paris
Local Institution - 007-1991
WITHDRAWN
Rennes
Local Institution - 007-198
NOT_YET_RECRUITING
Saint-herblain
Local Institution - 007-1990
NOT_YET_RECRUITING
Saint-herblain
Local Institution - 007-684
NOT_YET_RECRUITING
Strasbourg
Local Institution - 007-209
NOT_YET_RECRUITING
Tours
Local Institution - 007-202
NOT_YET_RECRUITING
Villejuif
Georgia
Local Institution - 007-790
WITHDRAWN
Batumi
Institute of Clinical Oncology - Tbilisi
RECRUITING
Tbilisi
Local Institution - 007-063
WITHDRAWN
Tbilisi
Local Institution - 007-065
WITHDRAWN
Tbilisi
Local Institution - 007-789
WITHDRAWN
Tbilisi
Local Institution - 007-795
WITHDRAWN
Tbilisi
Germany
Local Institution - 007-675
NOT_YET_RECRUITING
Amberg
Local Institution - 007-2222
NOT_YET_RECRUITING
Augsburg
Local Institution - Link, M.
NOT_YET_RECRUITING
Bad Homburg
Local Institution - Eggers, H.
NOT_YET_RECRUITING
Braunschweig
Klinikum Chemnitz
RECRUITING
Chemnitz
Local Institution - 007-2217
NOT_YET_RECRUITING
Cologne
Klinikum Esslingen
RECRUITING
Esslingen Am Neckar
Krankenhaus Nordwest
RECRUITING
Frankfurt Am Main
Universitatsklinikum Gieen und Marburg - Gieen
RECRUITING
Giessen
LungenClinic Grosshansdorf
RECRUITING
Grohansdorf
Local Institution - Erdmann, R.
NOT_YET_RECRUITING
Hamburg
Local Institution - 007-677
ACTIVE_NOT_RECRUITING
Heidelberg
Local Institution - 007-673
WITHDRAWN
Heilbronn
Lungenklinik Hemer
RECRUITING
Hemer
Local Institution - 007-211A
NOT_YET_RECRUITING
Immenstadt Im Allgäu
Local Institution - 007-225
WITHDRAWN
Jena
Local Institution - 007-2225
NOT_YET_RECRUITING
Kaiserslautern
Klinikum Kassel
RECRUITING
Kassel
Klinikverbund Allgau - Klinikum Kempten
RECRUITING
Kempten
Local Institution - 007-224
NOT_YET_RECRUITING
Löwenstein
Universitatsklinikum Schleswig-Holstein - Campus Lubeck
RECRUITING
Lübeck
Local Institution - 007-223
WITHDRAWN
Mainz
Local Institution - 007-2221
NOT_YET_RECRUITING
Mönchengladbach
Munchen Klinik Bogenhausen
RECRUITING
München
Local Institution - 007-2218
NOT_YET_RECRUITING
Neuruppin
Sana Klinikum Offenbach
RECRUITING
Offenbach
Pius-Hospital Oldenburg
RECRUITING
Oldenburg
Local Institution - 007-2219
NOT_YET_RECRUITING
Ulm
Greece
Local Institution - 007-236
NOT_YET_RECRUITING
Athens
Local Institution - 007-502
NOT_YET_RECRUITING
Athens
Local Institution - 007-506
NOT_YET_RECRUITING
Athens
Local Institution - 007-238
NOT_YET_RECRUITING
Heraklion
Local Institution - 007-235
NOT_YET_RECRUITING
Larissa
Local Institution - 007-237
NOT_YET_RECRUITING
Nea Kifissia
Metropolitan Hospital
RECRUITING
Piraeus
Saint Lukes Hospital
RECRUITING
Thessaloniki
Hong Kong Special Administrative Region
Humanity & Health Clinical Trial Centre
RECRUITING
Central
Local Institution - 007-044
NOT_YET_RECRUITING
Chai Wan
Queen Mary Hospital - Hong Kong
RECRUITING
Hong Kong
Local Institution - 007-045
NOT_YET_RECRUITING
Kowloon
Hungary
Orszagos Koranyi Pulmonologiai Intezet
RECRUITING
Budapest
Orszagos Onkologiai Intezet
RECRUITING
Budapest
Semmelweis Egyetem - Pulmonologiai Klinika
RECRUITING
Budapest
Farkasgyepui Tudogyogyintezet
RECRUITING
Farkasgyepű
Matrai Gyogyintezet
RECRUITING
Gyöngyös
Local Institution - 007-057
NOT_YET_RECRUITING
Tatabánya
Reformatus Pulmonologiai Centrum
RECRUITING
Törökbálint
India
Local Institution - 007-1568
NOT_YET_RECRUITING
Ahemdabad
Local Institution - 007-1574
NOT_YET_RECRUITING
Ahmedabad
Local Institution - 007-1565
NOT_YET_RECRUITING
Aurangabad
Local Institution - 007-1586
NOT_YET_RECRUITING
Bangalore
Local Institution - 007-1575
NOT_YET_RECRUITING
Belagavi
Local Institution - 007-1563
NOT_YET_RECRUITING
Hyderabad
Local Institution - 007-1564
WITHDRAWN
Hyderabad
Local Institution - 007-1569
NOT_YET_RECRUITING
Jaipur
Local Institution - 007-1566
NOT_YET_RECRUITING
Kochi
Local Institution - 007-1570
NOT_YET_RECRUITING
Kolkata
Local Institution - 007-1573
NOT_YET_RECRUITING
Madurai
Local Institution - Shetty, R.
NOT_YET_RECRUITING
Mangalore
Local Institution - 007-1582
NOT_YET_RECRUITING
Mumbai
Local Institution - 007-1561
NOT_YET_RECRUITING
Mysore
Local Institution - 007-1567
NOT_YET_RECRUITING
New Delhi
Local Institution - 007-1578
WITHDRAWN
New Delhi
Local Institution - 007-1560
NOT_YET_RECRUITING
Patna
Local Institution - 007-1571
NOT_YET_RECRUITING
Pune
Local Institution - 007-1562
NOT_YET_RECRUITING
Rajkot
Local Institution - 007-1581
NOT_YET_RECRUITING
Varanasi
Ireland
Local Institution - 007-256
WITHDRAWN
Cork
Beaumont Hospital - Dublin
RECRUITING
Dublin
Local Institution - 007-251
NOT_YET_RECRUITING
Dublin
St. Jamess Hospital
RECRUITING
Dublin
University Hospital Galway
RECRUITING
Galway
Local Institution - 007-258
WITHDRAWN
Limerick
University Hospital Waterford
RECRUITING
Waterford
Israel
Emek Medical Center
RECRUITING
Afula
Rambam Health Care Campus
RECRUITING
Bat Galim
Soroka Medical Center
RECRUITING
Beersheba
Local Institution - 007-263
WITHDRAWN
Holon
Hadassah University Hospital Ein Kerem
RECRUITING
Jerusalem
Shaare Zedek Medical Center
RECRUITING
Jerusalem
Kaplan Medical Center
RECRUITING
Rehovot
Tel Aviv Sourasky Medical Center
RECRUITING
Tel Aviv
Ziv Medical Center
RECRUITING
Zsfat
Italy
Local Institution - Unk016
ACTIVE_NOT_RECRUITING
Aviano
Istituto Tumori Bari Giovanni Paolo II - IRCCS
RECRUITING
Bari
Azienda Ospedaliero-Universitaria di Bologna - Policlinico Sant Orsola-Malpighi
RECRUITING
Bologna
Azienda Socio Sanitaria Territoriale (ASST) degli Spedali Civili di Brescia
RECRUITING
Brescia
Istituto di Candiolo - Fondazione del Piemonte per lOncologia
RECRUITING
Candiolo
Azienda Ospedaliero - Universitaria Careggi
RECRUITING
Florence
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale Policlinico San Martino
RECRUITING
Genova
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori - IRST
RECRUITING
Meldola
Fondazione IRCCS - Istituto Nazionale dei Tumori
RECRUITING
Milan
Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) - Ospedale San Raffaele
RECRUITING
Milan
Istituto Europeo di Oncologia
RECRUITING
Milan
Local Institution - 007-318
WITHDRAWN
Monza
Istituto Nazionale Tumori IRCCS Fondazione G. Pascale
RECRUITING
Napoli
Local Institution - Unk017
ACTIVE_NOT_RECRUITING
Padua
Azienda Ospedaliero-Universitaria di Parma
RECRUITING
Parma
Azienda Ospedaliera di Perugia - Santa Maria della Misericordia
RECRUITING
Perugia
Azienda Sanitaria Territoriale Pesaro Urbino
RECRUITING
Pesaro
Local Institution - 007-767
NOT_YET_RECRUITING
Ravenna
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
RECRUITING
Roma
Istituto Nazionale Tumori Regina Elena
RECRUITING
Roma
Local Institution - Unk030
ACTIVE_NOT_RECRUITING
Rozzano
Ospedale di Circolo e Fondazione Macchi
RECRUITING
Varese
Japan
Hyogo Cancer Center
RECRUITING
Akashi
Fukushima Medical University Hospital
RECRUITING
Fukushima
National Hospital Organization Iwakuni Clinical Center
RECRUITING
Iwakuni
Kanazawa University Hospital
RECRUITING
Kanazawa
Nara Medical University Hospital
RECRUITING
Kashihara
Nagasaki University Hospital
RECRUITING
Nagasaki
Jcho Chukyo Hospital
RECRUITING
Nagoya
National Hospital Organization - Nagoya Medical Center
RECRUITING
Nagoya
Kochi Medical School Hospital
RECRUITING
Nankoku-shi
Local Institution - 007-1593
NOT_YET_RECRUITING
Nishinomiya-shi
Osaka City General Hospital
RECRUITING
Osaka
Osaka Prefectural Hospital Organization - Osaka International Cancer Institute
RECRUITING
Osaka
Kitasato University Hospital
RECRUITING
Sagamihara
National Hospital Organization Kinki-Chuo Chest Medical Center
RECRUITING
Sakai-shi
Sendai Kousei Hospital
RECRUITING
Sendai
Ehime University Hospital
RECRUITING
Toon-shi
Local Institution - 007-1164
NOT_YET_RECRUITING
Toyama
Malaysia
Hospital Pulau Pinang
RECRUITING
George Town
Local Institution - Choo Khoon, O.
NOT_YET_RECRUITING
George Town
Local Institution - Unk048
ACTIVE_NOT_RECRUITING
George Town
Local Institution - Unk079
ACTIVE_NOT_RECRUITING
Johor Bahru
Hospital Kuala Lumpur
RECRUITING
Kuala Lumpur
Local Institution - Unk075
ACTIVE_NOT_RECRUITING
Kuala Lumpur
Local Institution - Unk007
ACTIVE_NOT_RECRUITING
Petaling Jaya
Sunway Medical Centre
RECRUITING
Petaling Jaya
Mexico
Local Institution - Unk070
ACTIVE_NOT_RECRUITING
Guadalajara
Local Institution - Unk034
ACTIVE_NOT_RECRUITING
Mexico City
Local Institution - Unk049
ACTIVE_NOT_RECRUITING
Mexico City
Local Institution - 007-477
NOT_YET_RECRUITING
Monterrey
Local Institution - Unk026
ACTIVE_NOT_RECRUITING
Monterrey
Local Institution - Unk037
ACTIVE_NOT_RECRUITING
Monterrey
Netherlands
Het Nederlands Kanker Instituut
RECRUITING
Amsterdam
Local Institution - 007-633
NOT_YET_RECRUITING
Dordrecht
Local Institution - 007-303
ACTIVE_NOT_RECRUITING
Harderwijk
Radboud Universitair Medisch Centrum
RECRUITING
Nijmegen
Erasmus Medisch Centrum
RECRUITING
Rotterdam
Franciscus Gasthuis & Vlietland - Gasthuis
RECRUITING
Rotterdam
Local Institution - 007-308
NOT_YET_RECRUITING
The Hague
Universitair Medisch Centrum Utrecht
RECRUITING
Utrecht
Local Institution - 007-305
WITHDRAWN
Zwolle
New Zealand
Local Institution - Anderson, M.
NOT_YET_RECRUITING
Palmerston North
Norway
Local Institution - 007-310
NOT_YET_RECRUITING
Drammen
Peru
Local Institution - Unk023
ACTIVE_NOT_RECRUITING
Arequipa
Local Institution - Unk044
ACTIVE_NOT_RECRUITING
Arequipa
Local Institution - Unk051
ACTIVE_NOT_RECRUITING
Arequipa
Local Institution - Unk040
ACTIVE_NOT_RECRUITING
Cusco
Local Institution - Unk022
ACTIVE_NOT_RECRUITING
Jesus Maria
Local Institution - Unk046
ACTIVE_NOT_RECRUITING
Lima
Local Institution - Unk031
ACTIVE_NOT_RECRUITING
Lima Cercado
Local Institution - Unk024
ACTIVE_NOT_RECRUITING
Miraflores
Local Institution - Unk042
ACTIVE_NOT_RECRUITING
San Isidro
Local Institution - Unk071
ACTIVE_NOT_RECRUITING
San Isidro
Local Institution - Unk054
ACTIVE_NOT_RECRUITING
Surquillo
Local Institution - Unk080
ACTIVE_NOT_RECRUITING
Trujillo
Philippines
Local Institution - 007-1541
WITHDRAWN
Bacolod City
Local Institution - 007-1545
WITHDRAWN
Cebu City
Local Institution - 007-1544
WITHDRAWN
Iloilo City
Local Institution - 007-1543
WITHDRAWN
Makati City
Local Institution - 007-1542
WITHDRAWN
Molo
Local Institution - 007-1540
WITHDRAWN
Quezon City
Poland
Uniwersyteckie Centrum Kliniczne w Gdansku
RECRUITING
Gdansk
Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej w Kielcach
RECRUITING
Kielce
Pratia MCM Krakow
RECRUITING
Krakow
MS Pneumed - Janusz Milanowski, Katarzyna Szmygin-Milanowska Spolka Jawna
RECRUITING
Lublin
Warminsko-mazurskie Centrum Chorob Pluc w Olsztynie
RECRUITING
Olsztyn
Mazowieckie Centrum Leczenia Chorob Pluc I Gruzlicy
RECRUITING
Otwock
Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeylandow
RECRUITING
Poznan
Pratia Poznan
RECRUITING
Skorzewo
Wojewodzki Szpital Zespolony im. L. Rydygiera w Toruniu
RECRUITING
Torun
Local Institution - 007-056
NOT_YET_RECRUITING
Warsaw
Local Institution - 007-322
WITHDRAWN
Warsaw
Portugal
Unidade Local de Saude de Coimbra
RECRUITING
Coimbra
Unidade Local de Saude do Alto Ave, E. P. E (Hospital da Senhora da Oliveira Guimaraes)
RECRUITING
Guimarães
Hospital CUF Descobertas
RECRUITING
Lisbon
Local Institution - 007-338-A
NOT_YET_RECRUITING
Lisbon
Local Institution - 007-642
NOT_YET_RECRUITING
Lisbon
Hospital CUF Porto
RECRUITING
Porto
Local Institution - 007-339
WITHDRAWN
Porto
Unidade Local de Saude de Santo Antonio, E. P. E - Hospital Geral de Santo Antonio
RECRUITING
Porto
Local Institution - 007-335
WITHDRAWN
Vila Nova De Gaia
Republic of Korea
Inje University Haeundae Paik Hospital
RECRUITING
Busan
Pusan National University Hospital
RECRUITING
Busan
Chungbuk National University Hospital
RECRUITING
Cheongju-si
Kyungpook National University Chilgok Hospital
RECRUITING
Daegu
National Cancer Center - Korea
RECRUITING
Goyang-si
Inha University Hospital
RECRUITING
Junggu
Asan Medical Center
RECRUITING
Seoul
Korea University Guro Hospital
RECRUITING
Seoul
Samsung Medical Center
RECRUITING
Seoul
Seoul National University Hospital
RECRUITING
Seoul
Severance Hospital
RECRUITING
Seoul
Catholic University of Korea St. Vincents Hospital
RECRUITING
Suwon
Romania
Institutul Oncologic Bucuresti - Prof. Dr. Alexandru Trestioreanu
RECRUITING
Bucharest
Medisprof
RECRUITING
Cluj-napoca
Centrul de Radioterapie Amethyst Cluj
RECRUITING
Floreşti
Centrul de Oncologie Euroclinic
RECRUITING
Iași
Oncocenter - Oncologie Clinica
RECRUITING
Timișoara
Serbia
Univerzitetski Klinicki Centar Srbije
RECRUITING
Belgrade
Institute for Pulmonary Diseases of Vojvodina
RECRUITING
Kamenitz
Local Institution - 007-694
NOT_YET_RECRUITING
Kragujevac
Uzice General Hospital
RECRUITING
Užice
Singapore
Curie Oncology - Farrer - 10-05
RECRUITING
Singapore
Raffles Hospital
RECRUITING
Singapore
South Africa
Local Institution - 007-4013
WITHDRAWN
Johannesburg
Local Institution - 007-4010
WITHDRAWN
Port Elizabeth
Local Institution - 007-4012
WITHDRAWN
Pretoria
Spain
Complejo Hospitalario Universitario A Coruna
RECRUITING
A Coruña
Institut Catala dOncologia Badalona
RECRUITING
Badalona
Hospital Clinic de Barcelona
RECRUITING
Barcelona
Hospital de la Santa Creu i Sant Pau
RECRUITING
Barcelona
Hospital Universitari Dexeus
RECRUITING
Barcelona
Hospital Universitari Vall dHebron
RECRUITING
Barcelona
Local Institution - Unk081
ACTIVE_NOT_RECRUITING
Bilbao
Local Institution - Unk063
ACTIVE_NOT_RECRUITING
Burgos
Local Institution - Unk014
ACTIVE_NOT_RECRUITING
Jerez De La Frontera
Complejo Hospitalario Universitario Insular Materno Infantil
RECRUITING
Las Palmas De Gran Canaria
Local Institution - Unk012
ACTIVE_NOT_RECRUITING
León
Institut Catala dOncologia - Hospital Duran i Reynals (ICO LHospitalet)
RECRUITING
Lhospitalet De Llobregat
Clinica Universidad de Navarra - Madrid
RECRUITING
Madrid
Hospital Clinico San Carlos
RECRUITING
Madrid
Hospital Universitario 12 de Octubre
RECRUITING
Madrid
Hospital Universitario Fundacion Jimenez Diaz
RECRUITING
Madrid
Hospital Universitario Ramon y Cajal
RECRUITING
Madrid
Hospital Regional Universitario de Malaga - Hospital Civil
RECRUITING
Málaga
Local Institution - 007-611 A
NOT_YET_RECRUITING
Pamplona
Local Institution - 007-604
WITHDRAWN
Santander
Hospital Clinico Universitario de Santiago
RECRUITING
Santiago De Compostela
Hospital Universitario Virgen del Rocio
RECRUITING
Seville
Hospital Clinico Universitario de Valencia
RECRUITING
Valencia
Hospital Universitari i Politecnic La Fe
RECRUITING
Valencia
Sweden
Local Institution - Unk013
ACTIVE_NOT_RECRUITING
Gävle
Switzerland
Local Institution - 007-397
WITHDRAWN
Sankt Gallen
Local Institution - 007-396
WITHDRAWN
Villars-sur-glâne
Taiwan
Local Institution - 007-127
WITHDRAWN
Taichung
Local Institution - 007-128
NOT_YET_RECRUITING
Taichung
Taichung Veterans General Hospital
RECRUITING
Taichung
Chi Mei Hospital - Liouying
RECRUITING
Tainan City
National Cheng Kung University Hospital
RECRUITING
Tainan City
National Taiwan University Hospital
RECRUITING
Taipei
Taipei Medical University - Shuang Ho Hospital, Ministry of Health and Welfare
RECRUITING
Taipei
Taipei Veterans General Hospital
RECRUITING
Taipei
Chang Gung Memorial Hospital - Linkou Branch
RECRUITING
Taoyuan District
Thailand
Local Institution - 007-139
NOT_YET_RECRUITING
Bangkok
Local Institution - Runglodvatana, Y.
NOT_YET_RECRUITING
Bangkok
Turkey
Baskent Universitesi Adana Uygulama Ve Arastirma Hastanesi
RECRUITING
Alanya
T.C. Saglik Bakanligi - Istanbul Il Saglik Mudurlugu - Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi
RECRUITING
Altındağ
Hacettepe Universitesi Kanser Enstitusu
RECRUITING
Ankara
Memorial Ankara Hastanesi
RECRUITING
Ankara
Local Institution - 007-3810
ACTIVE_NOT_RECRUITING
Antalya
Memorial Bahcelievler Hospital
RECRUITING
Bahçelievler
Local Institution - 007-060
NOT_YET_RECRUITING
Bornova
T.C. Saglik Bakanligi Ankara Bilkent Sehi�r Hastanesi�
RECRUITING
Çankaya
Trakya Universitesi Tip Fakultesi
RECRUITING
Edirne
Ozel Gaziantep Medical Point Hastanesi
RECRUITING
Gaziantep
Local Institution - 007-069
NOT_YET_RECRUITING
Istanbul
Local Institution - 007-3813
NOT_YET_RECRUITING
Istanbul
Izmir Ekonomi Universitesi Medical Point Hastanesi
RECRUITING
Izmir
Yeditepe Universitesi Kosuyolu Hastanesi
RECRUITING
Kadıköy
Kocaeli Universitesi Arastirma ve Uygulama Hastanesi
RECRUITING
Kocaeli
Inonu Universitesi Turgut Ozal Tip Merkezi
RECRUITING
Malatya
Ankara Universitesi Tip Fakultesi - Cebeci Arastirma ve Uygulama Hastanesi
RECRUITING
Mamak
Local Institution - 007-062
NOT_YET_RECRUITING
Şişli
United Kingdom
University Hospitals Birmingham NHS Foundation Trust
RECRUITING
Birmingham
Local Institution - 007-415
WITHDRAWN
Edinburgh
Local Institution - 007-403
NOT_YET_RECRUITING
Kent
University Hospitals of Leicester NHS Trust
RECRUITING
Leicester
Guys and St Thomas NHS Foundation Trust
RECRUITING
London
University College London Hospitals NHS Foundation Trust
RECRUITING
London
The Christie NHS Foundation Trust
RECRUITING
Manchester
Royal Surrey County Hospital NHS Foundation Trust
RECRUITING
Surrey
Contact Information
Primary
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
Clinical.Trials@bms.com
855-907-3286
Backup
First line of the email MUST contain the NCT# and Site #.
Time Frame
Start Date: 2020-12-02
Estimated Completion Date: 2029-10-31
Participants
Target number of participants: 806
Treatments
Experimental: Phase 2 Cohort 1a: PD-L1 TPS <1%
Cohort 1a: Adagrasib twice daily (BID) in combination with pembrolizumab
Experimental: Phase 2 Cohort 1b: PD-L1 TPS <1%
Cohort 1b: Adagrasib BID monotherapy
Experimental: Phase 2 Cohort 2: PD-L1 TPS ≥1%
Cohort 2: Adagrasib BID in combination with pembrolizumab
Experimental: Phase 3 Cohort 3 Investigational Arm
Adagrasib BID in combination with pembrolizumab
Active_comparator: Phase 3 Cohort 4 Comparator Arm
Pembrolizumab
Related Therapeutic Areas
Sponsors
Leads: Mirati Therapeutics Inc.