A Pilot Study to Assess the Diversity of Gut Microbiome in Metastatic Non-Small Cell Lung Cancer (NSCLC) in Correlation to Treatment Effects and Adverse Effects

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

This is a pilot study collecting data on the diversity and composition of gut microbiomes in subjects with advanced/metastatic Non-Small Cell Lung Cancer (NSCLC) while receiving treatment for NSCLC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• 1\. Advanced/Metastatic non-small cell lung cancer NSCLC patients.

• 2\. The patient himself/herself must be 18 years of age on day of signing informed consent.

• 3\. The subject has signed the informed consent form.

• 4\. The patient must be eligible to receive FDA approved and non-approved PD1 inhibitors (i.e. pembrolizumab, nivolumab) or PDL1 inhibitor (i.e. atezolizumab, durvalumab) either single agent or as combination therapy with chemotherapy, or be eligible to receive FDA approved and non-approved tyrosine kinase inhibitors.

• 5\. The subject will be registered upon submission of the samples. When submitted on separate dates, the submission occurring later will be considered the date of registration

Locations
United States
California
Chao Family Comprehensive Cancer Center University of California, Irvine
RECRUITING
Orange
Contact Information
Primary
Chao Family Comprehensive Cancer Center University of California, Irvine
ucstudy@uci.edu
1-877-827-8839
Backup
University of California Irvine Medical
Time Frame
Start Date: 2024-01-31
Estimated Completion Date: 2025-12
Participants
Target number of participants: 82
Treatments
Treatment with PD1/L1 monotherapy
Treatment with PD1/L1 + chemotherapy
Treatment with Tyrosine Kinase Inhibitor
Sponsors
Leads: University of California, Irvine

This content was sourced from clinicaltrials.gov