A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated Non-small Cell Lung Cancer (NSCLC)

Status: Recruiting
Location: See all (3) locations...
Study Type: Observational
SUMMARY

There are limited in depth studies on the epidemiology and clinical management of EGFR exon 20 insertion mutated NSCLC in Asia. In addition, there is preliminary data suggesting the exact location of the insertion and variant may influence the response and efficacy to novel EGFR targeted therapies. This study aims to fill this knowledge gap, by comprehensively characterising the epidemiology and clinical outcomes of Asian advanced EGFR exon 20 insertion mutated NSCLC patients.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 21
Maximum Age: 99
Healthy Volunteers: f
View:

• Histologically confirmed advanced NSCLC

• Positive testing result from any locally approved test (including but not limited to RT-PCR, Cobas and NGS) for EGFR exon 20 insertion mutation

• Diagnosis date from 1 Jan 2013 to 31 Dec 2024 (to allow for minimum 12 months of follow-up clinical and treatment outcome data)

• Male or female adults, age as defined by local regulations

Locations
Other Locations
Republic of Korea
Seoul National University Hospital
RECRUITING
Seoul
Singapore
National Cancer Centre, Singapore
RECRUITING
Singapore
Taiwan
National Taiwan University Hospital
RECRUITING
Taipei
Contact Information
Primary
Cherlyn Shepherdson
cherlyn.shepherdson@nccs.com.sg
+65 6306 1748
Time Frame
Start Date: 2024-03-15
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 600
Sponsors
Leads: National Cancer Centre, Singapore

This content was sourced from clinicaltrials.gov

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