Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

EGFR gene mutations are some of the most commonly occurring mutations in non-small cell lung cancer. Investigators have developed a DNA instability model that estimates a risk score to assess the likelihood of an individual acquiring a cancer-linked mutation. The aim of this study is to collect blood from both those diagnosed with EGFR positive lung cancer and healthy individuals, evaluate their gene sequence surrounding the EGFR landscape and use the cancer positive and healthy sequences to validate the risk assessment model, which may one day be used to provide insight on susceptibility of getting EGFR positive lung cancer or potentially other cancer types.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: t
View:

• 18-100 years old

• Biologically born female

• Diagnosed with EGFR positive lung cancer (Arm 1-Cancer group)

• No cancer diagnosis (Arm 2-health control)

Locations
United States
Louisiana
Our Lady of the Lake Regional Medical Center
RECRUITING
Baton Rouge
Contact Information
Primary
Cynthia Knox, MBA
Cynthia.Knox@fmolhs.org
225-765-3344
Backup
Christine LeBoeuf, DNP
Christine.Leboeuf@fmolhs.org
225-763-5956
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 20
Treatments
EGFR Positive Lung Cancer
Subjects diagnosed with EGFR positive lung cancer
Healthy Subjects
Subjects who do not have a cancer diagnosis
Sponsors
Leads: Our Lady of the Lake Hospital

This content was sourced from clinicaltrials.gov

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