A Multicenter, Open Phase IB/II Clinical Study of Safety, Tolerability, and Efficacy of SHR-1826 in Combination With Other Anti-cancer Treatment in Patients With Non-small Cell Lung Cancer

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1/Phase 2
SUMMARY

This is an open label, multi-center, multiple dose Phase IB/II study to evaluate the safety, tolerability and efficacy of SHR-1826 for injection in subjects with NSCLC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
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• Voluntary participation and written informed consent.

• 18-75 years older, no gender limitation.

• Eastern Cooperative Oncology Group (ECOG) score: 0-1.

• With a life expectancy ≥ 3 months.

• Pathologically diagnosed NSCLC.

• Be able to provide fresh or archived tumour tissue.

• At least one measurable lesion according to RECIST v1.1.

• Adequate organ function.

• Contraception is required during clinical trials, and pregnancy tests must be negative for women of childbearing age within 7 days before the first dose.

Locations
Other Locations
China
Shanghai Chest Hospital
RECRUITING
Shanghai
Contact Information
Primary
Yijun Jia
yijun.jia@hengrui.com
+86-18801784695
Backup
Tingting Lei
Tingting.lei.tl6@hengrui.com
+86-18610051325
Time Frame
Start Date: 2025-02-18
Estimated Completion Date: 2027-12
Participants
Target number of participants: 400
Treatments
Experimental: Experimental group
Sponsors
Leads: Suzhou Suncadia Biopharmaceuticals Co., Ltd.

This content was sourced from clinicaltrials.gov