A Randomized, Double-Blind, Phase 3 Trial of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated, Locally Advanced or Metastatic Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)
Status: Recruiting
Location: See all (329) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus platinum-doublet chemotherapy in participants with previously untreated, locally advanced or metastatic NSCLC with KRAS G12C mutation
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Histologically or cytologically confirmed diagnosis of non-squamous NSCLC with evidence of KRAS G12C mutation via tumor sample and/or circulating tumor deoxyribonucleic acid (ctDNA).
• Locally advanced or metastatic disease.
• Measurable disease via computed tomography (CT) or magnetic resonance imaging (MRI) per RECIST v1.1 criteria of at least 1 lesion.
• No prior systemic anti-cancer therapy given for advanced or metastatic disease.
• Not a candidate for definitive therapy (eg, chemoradiation or complete surgical resection).
• Participants with brain metastases are eligible for enrollment, including those with untreated brain metastases. Brain metastases must be asymptomatic and not in need of immediate local therapy. Any untreated brain metastases must be ≤ 20 mm in diameter.
• Any PD-L1 expression (0 to 100%) as determined by VENTANA PD-L1 (SP263) assay, Agilent PD-L1 IHC 22C3 pharmDx, or Agilent PD-L1 IHC 28-8 pharmDx.
Locations
United States
Alabama
Local Institution - 0347
NOT_YET_RECRUITING
Birmingham
California
Local Institution - 0581
NOT_YET_RECRUITING
Fullerton
Local Institution - 0202
NOT_YET_RECRUITING
Long Beach
Local Institution - 0643
NOT_YET_RECRUITING
Newport Beach
Local Institution - 0666
NOT_YET_RECRUITING
Orange
Local Institution - 0623
NOT_YET_RECRUITING
Santa Barbara
Colorado
Local Institution - 0442
NOT_YET_RECRUITING
Denver
Florida
Local Institution - 0651
NOT_YET_RECRUITING
Gainesville
Local Institution - 0621
NOT_YET_RECRUITING
Palm Bay
Local Institution - 0377
NOT_YET_RECRUITING
Tamarac
Local Institution - 0647
NOT_YET_RECRUITING
Tampa
Georgia
Local Institution - 0392
NOT_YET_RECRUITING
Fort Eisenhower
Local Institution - 0031
NOT_YET_RECRUITING
Marietta
Illinois
Local Institution - 0665
NOT_YET_RECRUITING
Arlington Heights
Indiana
Local Institution - 0423
NOT_YET_RECRUITING
Munster
Kentucky
Local Institution - 0366
NOT_YET_RECRUITING
Edgewood
Local Institution - 0566
NOT_YET_RECRUITING
Louisville
Louisiana
Local Institution - 0644
NOT_YET_RECRUITING
Shreveport
Massachusetts
Local Institution - 0019
NOT_YET_RECRUITING
Boston
Local Institution - 0437
NOT_YET_RECRUITING
Worcester
Maryland
Local Institution - 0385
NOT_YET_RECRUITING
Columbia
North Carolina
Local Institution - 0624
NOT_YET_RECRUITING
Asheville
Local Institution - 0672
NOT_YET_RECRUITING
Salisbury
New York
Local Institution - 0618
NOT_YET_RECRUITING
White Plains
Ohio
Local Institution - 0620
NOT_YET_RECRUITING
Columbus
Pennsylvania
Local Institution - 0657
NOT_YET_RECRUITING
York
South Carolina
Local Institution - 0658
NOT_YET_RECRUITING
Greenville
Texas
Local Institution - 0652
NOT_YET_RECRUITING
Laredo
Local Institution - 0622
NOT_YET_RECRUITING
San Antonio
Other Locations
Argentina
Hospital Italiano de Buenos Aires
RECRUITING
Abb
Local Institution - 0571
NOT_YET_RECRUITING
Buenos Aires
Clinica Adventista Belgrano
RECRUITING
Caba
Instituto Alexander Fleming
RECRUITING
Ciudad Autónoma De Buenos Aires
IDIM - Instituto de Investigaciones Metabólicas
RECRUITING
Ciudad De Buenos Aires
Local Institution - 0584
NOT_YET_RECRUITING
Pilar
Sanatorio Plaza
RECRUITING
Rosario
Australia
Princess Alexandra Hospital
RECRUITING
Brisbane
Canberra Hospital
RECRUITING
Canberra
Lyell McEwin Hospital
RECRUITING
Elizabeth Vale
Frankston Hospital
RECRUITING
Frankston
Joondalup Health Campus
RECRUITING
Joondalup
Northern Hospital
RECRUITING
Melbourne
Tamworth Hospital
RECRUITING
North Tamworth
Orange Hospital
RECRUITING
Orange
Latrobe Regional Health
RECRUITING
Traralgon
Austria
Medizinische Universität Graz
RECRUITING
Graz
Kepler Universitätsklinikum
RECRUITING
Linz
Local Institution - 0673
NOT_YET_RECRUITING
Vienna
Medizinische Universität Wien
RECRUITING
Vienna
Klinikum Wels-Grieskirchen GmbH
RECRUITING
Wels
Belgium
Cliniques universitaires Saint-Luc
RECRUITING
Brussels
UZ Brussel
RECRUITING
Brussels
AZ Maria Middelares
RECRUITING
Ghent
Jessa Ziekenhuis
RECRUITING
Hasselt
UZ Leuven
RECRUITING
Leuven
Centre Hospitalier Universitaire de Liège - Domaine Universitaire du Sart Tilman
RECRUITING
Liège
Brazil
Local Institution - 0240
NOT_YET_RECRUITING
Barretos
Local Institution - 0244
NOT_YET_RECRUITING
Belo Horizonte
Local Institution - 0237
NOT_YET_RECRUITING
Blumenau
Local Institution - 0235
NOT_YET_RECRUITING
Ijuí
Local Institution - 0245
NOT_YET_RECRUITING
Itajaí
Local Institution - 0233
NOT_YET_RECRUITING
Porto Alegre
Local Institution - 0243
NOT_YET_RECRUITING
Porto Velho
Local Institution - 0236
NOT_YET_RECRUITING
Rio De Janeiro
Local Institution - 0257
NOT_YET_RECRUITING
Salvador
Local Institution - 0238
NOT_YET_RECRUITING
Santa Cruz Do Sul
Local Institution - 0241
NOT_YET_RECRUITING
São Carlos
Local Institution - 0239
NOT_YET_RECRUITING
São José Do Rio Preto
Local Institution - 0254
NOT_YET_RECRUITING
São Paulo
Local Institution - 0258
NOT_YET_RECRUITING
São Paulo
Local Institution - 0242
NOT_YET_RECRUITING
Vitória
Bulgaria
Local Institution - 0629
NOT_YET_RECRUITING
Panagyurishte
Complex Oncology Center - Ruse EOOD
RECRUITING
Rousse
Local Institution - 0628
NOT_YET_RECRUITING
Sofia
Trakia Hospital
RECRUITING
Stara Zagora
Canada
Local Institution - 0074
NOT_YET_RECRUITING
Halifax
Local Institution - 0559
NOT_YET_RECRUITING
Montreal
Chile
Bradfordhill
RECRUITING
Recoleta
FALP
RECRUITING
Santiago
China
Beijing Cancer hospital
RECRUITING
Beijing
Beijing Chest Hospital,Capital Medical University
RECRUITING
Beijing
Beijing Peking Union Medical College Hospital
RECRUITING
Beijing
The First Afflilated Hospital of Bengbu Medical College
RECRUITING
Bengbu
The First Hospital of Jilin University
RECRUITING
Changchun
Local Institution - 0398
NOT_YET_RECRUITING
Changsha
Sichuan Cancer hospital
RECRUITING
Chengdu
West China Hospital, Sichuan University
RECRUITING
Chengdu
Chongqing University Cancer Hospital
RECRUITING
Chongqing
Fujian Medical University Union Hospital
RECRUITING
Fuzhou Fujian
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING
Guangzhou
The First Affiliated Hospital, Sun Yat-sen University
RECRUITING
Guangzhou
Local Institution - 0462
NOT_YET_RECRUITING
Hangzhou
Sir Run Run Shaw Hospital of Zhejiang University School of Medicine
RECRUITING
Hangzhou
Zhejiang Cancer Hospital
RECRUITING
Hangzhou
Harbin Medical University Cancer Hospital
RECRUITING
Harbin
Anhui Provincial Hospital
RECRUITING
Hefei
Shandong Cancer Hospital
RECRUITING
Jinan
LinYi Cancer Hospital
RECRUITING
Linyi
The Second Affiliated Hospital of Nanchang University
RECRUITING
Nanchang
Local Institution - 0371
NOT_YET_RECRUITING
Nanjing
Guangxi Medical University Affiliated Tumor Hospital
RECRUITING
Nanning
Nanyang City Center Hospital
RECRUITING
Nanyang
Local Institution - 0381
WITHDRAWN
Shanghai
Local Institution - 0470
NOT_YET_RECRUITING
Shanghai
Shanghai East Hospital
RECRUITING
Shanghai
Cancer Hospital of Shantou University Medical College
RECRUITING
Shantou
Local Institution - 0493
NOT_YET_RECRUITING
Shenyang
Shengjing Hospital of China Medical University
RECRUITING
Shenyang
The First Hospital of China Medical University
RECRUITING
Shenyang
Cancer Hospital Chinese Academy of Medical Sciences. Shenzhen Center
RECRUITING
Shenzhen
ShenZhen People's Hospital
RECRUITING
Shenzhen
Fourth Hospital of Hebei Medical University
RECRUITING
Shijiazhuang
The First Affiliated Hospital of Soochow University
RECRUITING
Suzhou
Shanxi Cancer Hospital
RECRUITING
Taiyuan
Taizhou Hospital of Zhejiang Province
RECRUITING
Taizhou
Tianjin Medical University General Hospital
RECRUITING
Tianjin
Tongji Hospital Tongji Medical,Science & Technology
RECRUITING
Wuhan
The First Affiliated hospital of Xiamen University
RECRUITING
Xiamen
The First Affiliated Hospital of Xinxiang Medical University
RECRUITING
Xinxiang
Northern Jiangsu People's Hospital
RECRUITING
Yangzhou
Colombia
Local Institution - 0671
NOT_YET_RECRUITING
Bogota
Local Institution - 0189
WITHDRAWN
Bogotá
Local Institution - 0170
NOT_YET_RECRUITING
Floridablanca
Local Institution - 0580
NOT_YET_RECRUITING
Medellín
Local Institution - 0167
NOT_YET_RECRUITING
Montería
Local Institution - 0191
WITHDRAWN
Puerto Colombia
Local Institution - 0171
NOT_YET_RECRUITING
Rionegro
Local Institution - 0173
NOT_YET_RECRUITING
Santiago De Cali
Local Institution - 0253
NOT_YET_RECRUITING
Valledupar
Croatia
Local Institution - 0619
NOT_YET_RECRUITING
Dubrovnik
Local Institution - 0567
NOT_YET_RECRUITING
Osijek
Local Institution - 0664
NOT_YET_RECRUITING
Rijeka
Local Institution - 0639
NOT_YET_RECRUITING
Split
Local Institution - 0585
NOT_YET_RECRUITING
Zagreb
France
CHU d'Amiens-Picardie - Hôpital Sud
RECRUITING
Amiens
Local Institution - 0560
NOT_YET_RECRUITING
Angers
Hôpital Ambroise Paré
RECRUITING
Boulogne-billancourt
CHRU de Brest
RECRUITING
Brest
Centre François Baclesse
RECRUITING
Caen
Chu Gabriel Montpied
RECRUITING
Clermont-ferrand
Centre Georges François Leclerc
RECRUITING
Dijon
Chu Grenoble Alpes
RECRUITING
La Tronche
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren
RECRUITING
Limoges
Assistance Publique Hôpitaux de Marseille - Hôpital Nord
RECRUITING
Marseille
Local Institution - 0636
NOT_YET_RECRUITING
Marseille
Institut Régional du Cancer Montpellier
RECRUITING
Montpellier
Local Institution - 0159
WITHDRAWN
Mulhouse
Hopitaux Universitaires Paris Centre-Hopital Cochin
RECRUITING
Paris
Local Institution - 0133
NOT_YET_RECRUITING
Paris
Hôpital Nord Guillaume-et-René-Laennec / CHU de Nantes
RECRUITING
Saint-herblain
Centre Hospitalier Régional Universitaire de Nancy - Hôpitaux de Brabois
RECRUITING
Vandœuvre-lès-nancy
Gustave Roussy
RECRUITING
Villejuif
Germany
Evangelische Lungenklinik Berlin
RECRUITING
Berlin
Vivantes Klinikum Neukölln
RECRUITING
Berlin
Klinikum Köln-Merheim
RECRUITING
Cologne
Klinikum Esslingen
RECRUITING
Esslingen Am Neckar
Malteser Krankenhaus St. Franziskus-Hospital
RECRUITING
Flensburg
Centrum für Hämatologie und Onkologie Bethanien
RECRUITING
Frankfurt Am Main
SRH Wald-Klinikum Gera GmbH
RECRUITING
Gera
UKGM Gießen/Marburg
RECRUITING
Giessen
Local Institution - 0675
NOT_YET_RECRUITING
Halle
Universitätsklinikum Halle
RECRUITING
Halle
Praxis Onkologie am Raschplatz
RECRUITING
Hanover
Local Institution - 0528
NOT_YET_RECRUITING
Hemer
Evangelisches Krankenhaus Herne - Eickel
RECRUITING
Herne
Universitätsklinikum Jena
RECRUITING
Jena
Klinikum der Ludwig-Maximilians-Universitaet Muenchen
RECRUITING
München
Pius Hospital Oldenburg
RECRUITING
Oldenburg
Local Institution - 0517
NOT_YET_RECRUITING
Stuttgart
Local Institution - 0670
NOT_YET_RECRUITING
Ulm
Universitaetsklinikum Wuerzburg
RECRUITING
Würzburg
Greece
Errikos Dunant Hospital Center
RECRUITING
Athens
Thoracic General Hospital of Athens I Sotiria
RECRUITING
Athens
University General Hospital of Larissa
RECRUITING
Larissa
Hong Kong Special Administrative Region
Queen Mary Hospital
RECRUITING
Hksar
Queen Mary Hospital
RECRUITING
Hksar
Hungary
Local Institution - 0151
NOT_YET_RECRUITING
Budapest
Országos Korányi Pulmonológiai Intézet
RECRUITING
Budapest
Local Institution - 0143
NOT_YET_RECRUITING
Farkasgyepű
Local Institution - 0144
NOT_YET_RECRUITING
Gyöngyös
Petz Aladar Egyetemi Oktato Korhaz
RECRUITING
Győr
Local Institution - 0593
NOT_YET_RECRUITING
Kaposvár
Local Institution - 0157
NOT_YET_RECRUITING
Tatabánya
India
Local Institution - 0136
NOT_YET_RECRUITING
Ahmedabad
Local Institution - 0230
NOT_YET_RECRUITING
Ahmedabad
Local Institution - 0226
NOT_YET_RECRUITING
Bhubaneswar
Local Institution - 0161
NOT_YET_RECRUITING
Howrah
Local Institution - 0661
NOT_YET_RECRUITING
Hyderabad
Local Institution - 0663
NOT_YET_RECRUITING
Hyderabad
Local Institution - 0221
NOT_YET_RECRUITING
Kolkata
Local Institution - 0224
NOT_YET_RECRUITING
Madurai
Local Institution - 0154
NOT_YET_RECRUITING
Mumbai
Local Institution - 0135
NOT_YET_RECRUITING
New Delhi
Local Institution - 0312
NOT_YET_RECRUITING
New Delhi
Local Institution - 0511
NOT_YET_RECRUITING
New Delhi
Local Institution - 0155
NOT_YET_RECRUITING
Thiruvananthapuram
Local Institution - 0153
NOT_YET_RECRUITING
Varanasi
Local Institution - 0222
NOT_YET_RECRUITING
Visakhapatnam
Ireland
Local Institution - 0102
NOT_YET_RECRUITING
Cork
Beaumont Hospital, Dublin
RECRUITING
Dublin
Local Institution - 0100
NOT_YET_RECRUITING
Dublin
Mater Private Hospital - Dublin
RECRUITING
Dublin
St. James's Hospital
RECRUITING
Dublin
Israel
Carmel Hospital
RECRUITING
Haifa
Hadassah Medical Center
RECRUITING
Jerusalem
Rabin Medical Center
RECRUITING
Petah Tikva
Sheba Medical Center
RECRUITING
Ramat Gan
Yitzhak Shamir Medical Center
RECRUITING
Ẕerifin
Italy
Local Institution - 0071
NOT_YET_RECRUITING
Bari
Azienda Ospedaliera Universitaria Careggi
RECRUITING
Florence
Ospedale San Martino
RECRUITING
Genova
IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) Dino Amadori
RECRUITING
Meldola
A.O.R.N. Ospedale dei Colli - Monaldi V.
RECRUITING
Naples
Local Institution - 0070
NOT_YET_RECRUITING
Orbassano
Local Institution - 0073
NOT_YET_RECRUITING
Padua
Local Institution - 0156
NOT_YET_RECRUITING
Parma
Local Institution - 0543
NOT_YET_RECRUITING
Pavia
Istituto Nazionale Tumori Regina Elena
RECRUITING
Rome
Local Institution - 0556
NOT_YET_RECRUITING
Varese
Japan
Local Institution - 0307
NOT_YET_RECRUITING
Akashi
Local Institution - 0346
NOT_YET_RECRUITING
Aomori
Local Institution - 0674
NOT_YET_RECRUITING
Bunkyo Ku
Local Institution - 0310
NOT_YET_RECRUITING
Fukuoka
Local Institution - 0367
NOT_YET_RECRUITING
Fukushima
Local Institution - 0606
NOT_YET_RECRUITING
Hamamatsu
Local Institution - 0303
NOT_YET_RECRUITING
Hidaka
Local Institution - 0642
NOT_YET_RECRUITING
Hirakata
Local Institution - 0300
NOT_YET_RECRUITING
Ina-machi
Local Institution - 0542
NOT_YET_RECRUITING
Iwakuni
Local Institution - 0304
NOT_YET_RECRUITING
Kanazawa
Local Institution - 0306
NOT_YET_RECRUITING
Kashihara
Local Institution - 0308
NOT_YET_RECRUITING
Kumamoto
Local Institution - 0368
NOT_YET_RECRUITING
Kurashiki
Local Institution - 0305
NOT_YET_RECRUITING
Nagoya
Local Institution - 0607
NOT_YET_RECRUITING
Nagoya
Local Institution - 0297
NOT_YET_RECRUITING
Osaka
Local Institution - 0309
NOT_YET_RECRUITING
Osaka
Local Institution - 0302
NOT_YET_RECRUITING
Sagamihara
Local Institution - 0298
NOT_YET_RECRUITING
Sapporo
Local Institution - 0301
NOT_YET_RECRUITING
Sendai
Local Institution - 0299
NOT_YET_RECRUITING
Shimotsuga
Local Institution - 0343
NOT_YET_RECRUITING
Toyoma
Local Institution - 0369
NOT_YET_RECRUITING
Yokohama
Mexico
Local Institution - 0175
NOT_YET_RECRUITING
Chihuahua City
Local Institution - 0178
NOT_YET_RECRUITING
Guadalajara
Local Institution - 0176
NOT_YET_RECRUITING
Mexico City
Local Institution - 0591
NOT_YET_RECRUITING
Monterrey
Local Institution - 0579
NOT_YET_RECRUITING
Pachuca
Local Institution - 0181
NOT_YET_RECRUITING
Puebla City
Local Institution - 0638
NOT_YET_RECRUITING
Puebla City
Local Institution - 0583
NOT_YET_RECRUITING
Saltillo
Local Institution - 0180
NOT_YET_RECRUITING
Veracruz
Netherlands
Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL)
RECRUITING
Amsterdam
Local Institution - 0615
NOT_YET_RECRUITING
Maastricht
Poland
Centrum Onkologii im. Prof. Franciszka Lukaszczyka
RECRUITING
Bydgoszcz
Szpital Specjalistyczny im. Henryka Klimontowicza
RECRUITING
Gorlice
Pratia Onkologia Katowice
RECRUITING
Katowice
Pratia MCM Krakow
RECRUITING
Krakow
Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie
RECRUITING
Lublin
Med-Polonia Sp. z o. o.
RECRUITING
Poznan
Szpital Specjalistyczny w Prabutach Spolka z o.o.
RECRUITING
Prabuty
Local Institution - 0205
NOT_YET_RECRUITING
Wroclaw
Portugal
Instituto Portugês de Oncologia de Coimbra Francisco Gentil
RECRUITING
Coimbra
Local Institution - 0509
NOT_YET_RECRUITING
Lisbon
Centro Hospitalar do Porto - Hospital de Santo António
RECRUITING
Porto
Republic of Korea
Pusan National University Hospital
RECRUITING
Busan
Chungbuk National University Hospital
RECRUITING
Cheongju-si
Gachon University Gil Medical Center
RECRUITING
Namdong-gu
Konkuk University Medical Center
RECRUITING
Seoul
Korea University Guro Hospital
RECRUITING
Seoul
Severance Hospital, Yonsei University Health System
RECRUITING
Seoul
The Catholic Univ. of Korea Seoul St. Mary's Hospital
RECRUITING
Seoul
Pusan National University Yangsan Hospital
RECRUITING
Yangsan
Romania
Institutul Oncologic Bucuresti
RECRUITING
Bucharest
SC Memorial Healthcare International SRL
RECRUITING
Bucharest
Cardiomed SRL Cluj-Napoca
RECRUITING
Cluj-napoca
Institutul Oncologic Cluj
RECRUITING
Cluj-napoca
Institutul Oncologic Cluj
RECRUITING
Cluj-napoca
Affidea Constanța
RECRUITING
Constanța
Centrul de Oncologie Sfântul Nectarie
RECRUITING
Craiova
SC Radiotherapy Center Cluj SRL
RECRUITING
Florești
Institutul Regional de Oncologie
RECRUITING
Iași
S.C. Centrul de Oncologie Euroclinic S.R.L.
RECRUITING
Iași
Ovidius Clinical Hospital OCH
RECRUITING
Ovidiu
Spitalul Municipal Schuller Ploiești
RECRUITING
Ploieşti
Cabinet Medical Oncomed
RECRUITING
Timișoara
Saudi Arabia
Local Institution - 0614
NOT_YET_RECRUITING
Jeddah
Local Institution - 0562
NOT_YET_RECRUITING
Riyadh
Local Institution - 0602
NOT_YET_RECRUITING
Riyadh
Spain
CHUAC-Hospital Teresa Herrera
RECRUITING
A Coruña
Hospital Universitari Vall d'Hebron
RECRUITING
Barcelona
Local Institution - 0505
WITHDRAWN
Barcelona
Local Institution - 0497
WITHDRAWN
Hospitalet
Hospital Clinico San Carlos
RECRUITING
Madrid
Hospital General Universitario Gregorio Marañon
RECRUITING
Madrid
Hospital Universitario 12 de Octubre
RECRUITING
Madrid
Hospital Universitario Ramón y Cajal
RECRUITING
Madrid
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING
Majadahonda
H.R.U Málaga - Hospital General
RECRUITING
Málaga
Hospital Son Llàtzer
RECRUITING
Palma
Local Institution - 0669
NOT_YET_RECRUITING
Pontevedra
CHUS - Hospital Clinico Universitario
RECRUITING
Santiago De Compostela
Hospital Universitario Virgen Del Rocio
RECRUITING
Seville
Hospital Arnau de Vilanova
RECRUITING
Valencia
Local Institution - 0495
WITHDRAWN
Valencia
Switzerland
Kantonsspital Münsterlingen - Spital Thurgau AG
RECRUITING
Münsterlingen
Taiwan
Taipei Medical University Shuang Ho Hospital
RECRUITING
New Taipei City
Chi Mei Hospital - Liouying Branch
RECRUITING
Tainan City
National Cheng Kung University Hospital
RECRUITING
Tainan City
National Taiwan University Hospital
RECRUITING
Taipei
Tri-Service General Hospital
RECRUITING
Taipei City
Thailand
Local Institution - 0563
NOT_YET_RECRUITING
Bangkok
Local Institution - 0564
NOT_YET_RECRUITING
Hat Yai
Local Institution - 0565
NOT_YET_RECRUITING
Muang
Turkey
Local Institution - 0197
NOT_YET_RECRUITING
Adana
Local Institution - 0194
NOT_YET_RECRUITING
Ankara
Local Institution - 0198
NOT_YET_RECRUITING
Ankara
Local Institution - 0201
NOT_YET_RECRUITING
Ankara
Local Institution - 0549
NOT_YET_RECRUITING
Istanbul
Local Institution - 0550
NOT_YET_RECRUITING
Istanbul
Local Institution - 0200
NOT_YET_RECRUITING
Izmir
Local Institution - 0199
NOT_YET_RECRUITING
Izmir, Karsiyaka
Local Institution - 0548
NOT_YET_RECRUITING
Stanbul
United Kingdom
Heartlands Hospital
RECRUITING
Birmingham
Local Institution - 0545
WITHDRAWN
Guildford
The Royal Surrey County Hospital
RECRUITING
Guildford
Guy's & St Thomas' NHS Foundation Trust
RECRUITING
London
University College London Hospital
RECRUITING
London
Local Institution - 0093
WITHDRAWN
Manchester
Contact Information
Primary
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
Clinical.Trials@bms.com
855-907-3286
Backup
First line of the email MUST contain the NCT# and Site #.
Time Frame
Start Date: 2025-04-24
Estimated Completion Date: 2032-04-30
Participants
Target number of participants: 630
Treatments
Experimental: Adagrasib
Placebo_comparator: Placebo
Related Therapeutic Areas
Sponsors
Leads: Mirati Therapeutics Inc.