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Prediction in Silico of Therapeutic Response in a Prospective Cohort Study of Metastatic Lung Cancer Patients

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

RATIONALE : Currently, the mechanisms associated with the response or resistance to treatment are poorly understood and are multifactorial. These mechanisms involve clinical and biological factors associated with the host and the tumor and possibly the patient's psycho-social environment. PURPOSE : This trial will assess the use of a prospective database dedicated to patients with breast cancers that contains clinical data as well as epidemiological, psychological, emotional, social, imaging, biological and biopathological data. These data will allow a creation of new modelling algorithms in order to predict response and resistance to treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Written informed consent obtained from the patient prior to performing any protocol-related procedures, including screening biopsy, blood sample and questionnaires

• 18 years old at time of written consent

• Patient with histologically confirmed lung cancer

• Lung cancer metastatic disease or locally advanced not eligible for local curative treatment intent

• Performance status ≤ 2 (according to WHO criteria)

• Indication of any systemic therapeutic strategy can be performed alongside this current cohort in accordance with national and / or international recommendations.

• Patient is willing and able to comply with the protocol for the duration of the study including undergoing treatment and scheduled visits and examinations including follow up.

• Patient must be affiliated to a Social Health Insurance

Locations
Other Locations
France
Institut de Cancerologie de L'Ouest
RECRUITING
Angers
Institut de Cancerologie de L'Ouest
RECRUITING
Saint-herblain
Contact Information
Primary
JUDITH RAIMBOURG, MD,PHD
judith.raimbourg@ico.unicancer.fr
0240679900
Backup
MARINE TIGREAT
marine.tigreat@ico.unicancer.fr
0240679878
Time Frame
Start Date: 2023-04-24
Estimated Completion Date: 2031-10
Participants
Target number of participants: 200
Treatments
Other: Follow
At each disease progression, patient will have specific interventions :~* Metastasis biopsy~* Biomarkers blood, urine and microbiota samples~* Patient Reported Outcome (PRO)
Related Therapeutic Areas
Sponsors
Leads: Institut Cancerologie de l'Ouest

This content was sourced from clinicaltrials.gov