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To Evaluate the Effectiveness and Safety of Stereotactic Radiotherapy (SBRT) in the Treatment of Patients With Residual Malignant Pulmonary Nodules After Lung Cancer Surgery: A Multi-center, Prospective Clinical Trial (SMILE)

Status: Recruiting
Location: See all (5) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY

To prospectively evaluate the effectiveness and safety of SBRT in the treatment of residual malignant pulmonary nodules after lung cancer, and is committed to providing new treatment options for patients with multiple primary malignant pulmonary nodules who cannot tolerate multiple operations.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• (1) Age 18-75 years old; (2) ECOG score 0-2 points; (3) Chest CT showed at least two lung nodules (pure ground glass, partial solid or solid nodules); (4) At least one lesion has been pathologically diagnosed as lung cancer (T1N0M0-T1N1M0); (5) At least one residual pulmonary nodule has been diagnosed pathologically or multidisciplinary diagnosis and treatment (MDT) discussed and considered as a primary malignant pulmonary nodule; (6) The residual lung nodules are inoperable or operable but the patient refuses to be surgically removed; (7) Have self-consciousness and can sign informed consent; (8) Must be able to swallow tablets.

Locations
Other Locations
China
Hunan Cancer Hospital
RECRUITING
Changsha
Oncology Department,Second Xiangya Hospital of Central South University
RECRUITING
Changsha
The Third Xiangya Hospital, Central South University
RECRUITING
Changsha
Xiangya Hospital, Central South University
RECRUITING
Changsha
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITING
Wuhan
Contact Information
Primary
Chunhong Hu, professor
huchunh5829@126.com
+86 13508486908
Time Frame
Start Date: 2021-07-01
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 40
Treatments
SBRT group
Patients with residual lung nodules are treated with SBRT
Related Therapeutic Areas
Sponsors
Collaborators: Hunan Cancer Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University
Leads: Fang Wu

This content was sourced from clinicaltrials.gov