A Phase 3, Multicenter, Randomized, Open-label Study Evaluating Efficacy of Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Subjects With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers, Negative for PD-L1, and Positive for KRAS p.G12C (CodeBreaK 202)
Status: Recruiting
Location: See all (370) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY
The primary objectives are to compare progression-free survival (PFS) and overall survival (OS) in participants who receive sotorasib with platinum doublet chemotherapy versus participants who receive pembrolizumab with platinum doublet chemotherapy.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:
• Histologically or cytologically confirmed diagnosis of nonsquamous stage IV or advanced Stage IIIB or IIIC NSCLC with KRAS p. G12C mutation and negative for PD-L1 expression by central testing or local laboratory testing confirmed through central testing
• No history of systemic anticancer therapy in metastatic/non-curable settings
• Eastern Cooperative Oncology Group (ECOG) ≤ 1
Locations
United States
California
Sansum Clinic
RECRUITING
Santa Barbara
Delaware
Medical Oncology Hematology Consultants Helen F Graham Cancer Center
RECRUITING
Newark
Illinois
University of Illinois Chicago
RECRUITING
Chicago
Illinois Cancer Specialists
RECRUITING
Niles
Kentucky
Norton Cancer Institute - Brownsboro
COMPLETED
Louisville
Massachusetts
Reliant Medical Group Inc
RECRUITING
Worcester
North Carolina
Duke University
RECRUITING
Durham
FirstHealth Cancer Center
RECRUITING
Pinehurst
New Mexico
University of New Mexico Cancer Center
RECRUITING
Albuquerque
New York
Memorial Sloan Kettering Cancer Center
TERMINATED
New York
Pennsylvania
Alliance Cancer Specialists - Media
RECRUITING
Media
University of Pittsburgh Medical Center
TERMINATED
Pittsburgh
Tennessee
University of Tennessee Medical Center Knoxville
RECRUITING
Knoxville
Regional One Health
RECRUITING
Memphis
Sarah Cannon Research Institute
RECRUITING
Nashville
United States Oncology Regulatory Affairs Corporate Office
RECRUITING
Nashville
Texas
University of Texas MD Anderson Cancer Center
RECRUITING
Houston
US Oncology Research Investigational Products Center
RECRUITING
Irving
Other Locations
Argentina
Centro Oncologico Korben
RECRUITING
Buenos Aires
Hospital Britanico de Buenos Aires
RECRUITING
Caba
Instituto Alexander Fleming
RECRUITING
Capital Federal
Instituto Argentino de Diagnostico y Tratamiento IADT
RECRUITING
Ciudad Autónoma De Buenos Aires
Hospital Italiano de La Plata
RECRUITING
La Plata
Fundacion Centro Oncológico Riojano Integral para la Investigación y Prevención del Cáncer
RECRUITING
La Rioja
Sanatorio Parque SA
RECRUITING
Rosario
Centro de Diagnostico Investigacion y Tratamiento
RECRUITING
Salta
Fundacion Ars Medica
RECRUITING
San Salvador De Jujuy
Clinica Viedma
RECRUITING
Viedma
Australia
Cancer Research South Australia
RECRUITING
Adelaide
Campbelltown Hospital
RECRUITING
Campbelltown
Concord Repatriation General Hospital
RECRUITING
Concord
Nepean Cancer Centre
RECRUITING
Kingswood
Peter MacCallum Cancer Centre
RECRUITING
Melbourne
The Alfred Hospital
RECRUITING
Melbourne
GenesisCare -North Shore Oncology
RECRUITING
St Leonards
Toowoomba Hospital
RECRUITING
Toowoomba
Calvary Mater Newcastle Hospital
RECRUITING
Waratah
Princess Alexandra Hospital
RECRUITING
Woolloongabba
Austria
Medizinische Universitaet Graz
RECRUITING
Graz
Klinikum Klagenfurt am Woerthersee
RECRUITING
Klagenfurt
Universitaetsklinikum Krems
RECRUITING
Krems
Landeskrankenhaus Salzburg
COMPLETED
Salzburg
Klinikum Wels - Grieskirchen GmbH
RECRUITING
Wels
Belgium
Chirec - Delta Ziekenhuis
RECRUITING
Auderghem
Algemeen Ziekenhuis Maria Middelares
RECRUITING
Ghent
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
RECRUITING
Leuven
Centre Hospitalier Regional de la Citadelle
RECRUITING
Liège
Algemeen Ziekenhuis Sint-Maarten
RECRUITING
Mechelen
Brazil
Fundacao Pio Xii Barretos
RECRUITING
Barretos
Centro de Tratamento Oncologico - Cto
RECRUITING
Belém
Nucleo de Ensino Pesquisa e Inovacao Mario Penna
RECRUITING
Belo Horizonte
Hospital Sirio Libanes
RECRUITING
Brasília
Oncoclinicas Onco Vida Distrito Federal
RECRUITING
Brasília
Hospital Evangelico de Cachoeiro de Itapemirim
RECRUITING
Cachoeiro De Itapemirim
Associação Beneficente de Canoas
TERMINATED
Canoas
Clinica de Neoplasias Litoral
TERMINATED
Itajaí
Liga Norte-Riograndense Contra O Cancer
RECRUITING
Natal
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
RECRUITING
Porto Alegre
Irmandade da Santa Casa de Misericordia de Porto Alegre
RECRUITING
Porto Alegre
Instituto Medicina Integral Imip
RECRUITING
Recife
Oncoclinicas Rio de Janeiro S A
RECRUITING
Rio De Janeiro
Núcleo de Oncologia da Bahia
RECRUITING
Salvador
Centro de pesquisa em oncologia Hospital Ana Nery
RECRUITING
Santa Cruz Do Sul
Santa Casa de Misericordia de Santos - Iscms
RECRUITING
Santos
Hospital de Base de Sao Jose do Rio Preto
RECRUITING
São José Do Rio Preto
Beneficencia Portuguesa de Sao Paulo - Bp
RECRUITING
São Paulo
Fundacao Antonio Prudente
RECRUITING
São Paulo
Instituto Cancer Sao Paulo Icesp
RECRUITING
São Paulo
Instituto de Ensino e Pesquisa Sao Lucas Iep Sao Lucas
RECRUITING
São Paulo
Bulgaria
Multiprofile Hospital for Active Treatment - Uni Hospital OOD
RECRUITING
Panagyurishte
University Multiprofile Hospital for Active Treatment Sveta Marina - Pleven OOD
RECRUITING
Pleven
Acibadem City Clinic University Multiprofile Hospital for Active Treatment Tokuda EAD
RECRUITING
Sofia
Multiprofile Hospital for Active Treatment for Womens Health - Nadezhda OOD
RECRUITING
Sofia
University Multiprofile Hospital for Active Treatment Tsaritsa Yoanna - ISUL EAD
TERMINATED
Sofia
Canada
Queen Elizabeth II, Health Sciences Centre
RECRUITING
Halifax
CIUSSS - du Nord-de-lIle-de-Montreal / Hopital Sacre-Coeur de Montreal
RECRUITING
Montreal
McGill University Health Centre Glen Site
RECRUITING
Montreal
Institut Universitaire de cardiologie et de pneumologie de Quebec
RECRUITING
Québec
Allan Blair Cancer Centre
RECRUITING
Regina
Saskatoon Cancer Centre
RECRUITING
Saskatoon
Sunnybrook Research Institute Sunnybrook Health Sciences Centre
RECRUITING
Toronto
Chile
Biocinetic servicios medicos limitada
RECRUITING
Santiago
Fundacion Arturo Lopez Perez
RECRUITING
Santiago
Orlandi Oncologia
RECRUITING
Santiago
Centro de Investigacion del Maule
RECRUITING
Talca
Clinica CIDO
RECRUITING
Temuco
James Lind Centro de Investigacion del Cancer
RECRUITING
Temuco
China
AnYang Tumor Hospital
RECRUITING
Anyang
Affiliated Hospital of Hebei University
RECRUITING
Baoding
Beijing Cancer Hospital
RECRUITING
Beijing
Beijing Chest Hospital, Capital Medical University
RECRUITING
Beijing
Peking Union Medical College Hospital
RECRUITING
Beijing
The First Affiliated Hospital of Bengbu Medical University
RECRUITING
Bengbu
Jilin Cancer Hospital
RECRUITING
Changchun
Hunan Cancer Hospital
RECRUITING
Changsha
Hunan Cancer Hospital
RECRUITING
Changsha
The Second Xiangya Hospital of Central South University
RECRUITING
Changsha
Xiangya Hospital Central South University
RECRUITING
Changsha
Sichuan Cancer Hospital
RECRUITING
Chengdu
West China Hospital of Sichuan University
RECRUITING
Chengdu
Chongqing University Cancer Hospital
RECRUITING
Chongqing
Fujian Cancer Hospital
RECRUITING
Fuzhou
Fujian Medical University Union Hospital
RECRUITING
Fuzhou
Fujian Provincial Hospital
RECRUITING
Fuzhou
Affiliated Cancer Hospital and institute of Guangzhou Medical University
RECRUITING
Guangzhou
Guangdong Provincial Peoples Hospital
RECRUITING
Guangzhou
Hainan Cancer Hospital
RECRUITING
Haikou
Sir Run Run Shaw Hospital Affiliated to Zhejiang University School of Medicine
RECRUITING
Hangzhou
the First Affiliated Hospital Zhejiang University School of Medicine
RECRUITING
Hangzhou
Zhejiang Cancer Hospital
RECRUITING
Hangzhou
Harbin Medical University Cancer Hospital
RECRUITING
Harbin
Anhui Chest Hospital
RECRUITING
Hefei
Cancer Hospital of Shandong First Medical University
RECRUITING
Jinan
Yunnan Cancer Hospital
RECRUITING
Kunming
Gansu Province Cancer Hospital
RECRUITING
Lanzhou
Linyi Peoples Hospital
RECRUITING
Linyi
Liuzhou Peoples Hospital
RECRUITING
Liuzhou
The First Affiliated Hospital of Henan University of Science And Technology
RECRUITING
Luoyang
Jiangxi Cancer Hospital
RECRUITING
Nanchang
The First Affiliated Hospital of Nanchang University
RECRUITING
Nanchang
Nanjing Drum Tower Hospital
RECRUITING
Nanjing
Nanjing First Hospital
RECRUITING
Nanjing
Guangxi Medical University Cancer Hospital
RECRUITING
Nanning
Nantong Tumor Hospital
RECRUITING
Nantong
Fudan University Shanghai Cancer Center
RECRUITING
Shanghai
Cancer Hospital of Shantou University Medical College
RECRUITING
Shantou
Shanxi Cancer Hospital
RECRUITING
Taiyuan
Taizhou Hospital of Zhejiang Province
RECRUITING
Taizhou
Tianjin Medical University Cancer Institute and Hospital
RECRUITING
Tianjin
Weifang Peoples Hospital
RECRUITING
Weifang
Tongji Hospital Tongji Medical College Of Hust
RECRUITING
Wuhan
Union Hospital Tongji Medical College Huazhong University of Science and Technology
RECRUITING
Wuhan
The First Affiliated Hospital of Xi An JiaoTong University
RECRUITING
Xi’an
The First Affiliated Hospital of Xiamen University
RECRUITING
Xiamen
Zhongshan Hospital Xiamen University
RECRUITING
Xiamen
Xiangyang Central Hospital
RECRUITING
Xiangyang
Henan Cancer Hospital
RECRUITING
Zhengzhou
The First Affiliated Hospital of Zhengzhou University
RECRUITING
Zhengzhou
Colombia
Centro Cancerologico del Caribe LTDA CECAC
RECRUITING
Barranquilla
Instituto Nacional de Cancerologia
RECRUITING
Bogota
Centro de Tratamiento e Investigación sobre Cancer Luis Carlos Sarmiento Angulo Ctic
RECRUITING
Bogotá
Fundacion cardiovascular de Colombia
RECRUITING
Bucaramanga
Fundacion Colombiana de Cancerologia Clinica Vida
RECRUITING
Medellín
Instituto Medico de Alta Tecnologia sas - Imat sas
RECRUITING
Montería
Oncologos del Occidente SAS
RECRUITING
Pereira
Sociedad de Oncologia y Hematologia del Cesar
RECRUITING
Valledupar
Denmark
Aarhus Universitetshospital
RECRUITING
Aarhus N
Rigshospitalet
RECRUITING
Copenhagen
Regionshospitalet Godstrup
RECRUITING
Herning
Sonderborg Sygehus
RECRUITING
Sønderborg
Vejle Sygehus
RECRUITING
Vejle
France
Centre Hospitalier Regional Universitaire de Besancon - Hopital Jean Minjoz
RECRUITING
Besançon
Centre Hospitalier Universitaire Ambroise Pare
RECRUITING
Boulogne-billancourt
Centre Hospitalier Universitaire de Caen - Hopital Cote de Nacre
RECRUITING
Caen
Centre Hospitalier Intercommunal de Creteil
RECRUITING
Créteil
Centre Hospitalier Departemental Les Oudairies
RECRUITING
La Roche-sur-yon
Centre Hospitalier - Le Mans
RECRUITING
Le Mans
Centre Hospitalier Régional Universitaire de Lille - Institut Coeur Poumon
RECRUITING
Lille
Centre Hospitalier Universitaire Nord
RECRUITING
Marseille
Centre de Cancerologie du Grand Montpellier-Clinique Clementville
RECRUITING
Montpellier
Hopital prive du Confluent
RECRUITING
Nantes
Centre Antoine Lacassagne
RECRUITING
Nice
Hopital Universitaire Caremeau
RECRUITING
Nîmes
Groupe Hospitalier Paris Saint Joseph
RECRUITING
Paris
Hopital Cochin
RECRUITING
Paris
Hopital Tenon
RECRUITING
Paris
Institut Curie
RECRUITING
Paris
Centre Hospitalier Universitaire de Bordeaux - Hopital Haut Leveque
RECRUITING
Pessac
Centre Hospitalier Universitaire de Poitiers - Hopital la Miletrie
RECRUITING
Poitiers
Centre Hospitalier de Cornouaille
RECRUITING
Quimper
Centre Hospitalier Universitaire de Reims - Hopital Christian Cabrol
RECRUITING
Reims
Centre Hospitalier Universitaire de Rennes - Hopital Pontchaillou
RECRUITING
Rennes
Centre Hospitalier Universitaire de Rouen - Hopital Charles Nicolle
RECRUITING
Rouen
Centre Hospitalier Universitaire de Saint Etienne - Hopital Nord
RECRUITING
Saint-priest-en-jarez
Centre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil
RECRUITING
Strasbourg
Hopital d instruction des armees sainte anne
RECRUITING
Toulon
Centre Hospitalier Universitaire de Toulouse - Hopital Larrey
RECRUITING
Toulouse
Centre Hospitalier Regional Universitaire de Tours - Hopital Bretonneau
RECRUITING
Tours
Hopital Nord Ouest Villefranche sur Saone
RECRUITING
Villefranche-sur-saône
Gustave Roussy
RECRUITING
Villejuif
Germany
Klinikum Chemnitz GmbH
RECRUITING
Chemnitz
Asklepios Fachkliniken Muenchen Gauting
RECRUITING
Gauting
Universitaetsmedizin Goettingen
RECRUITING
Göttingen
Klinikverbund Allgaeu
RECRUITING
Kempten
Klinikum der LMU Muenchen
RECRUITING
München
Greece
251 General Airforce Hospital
RECRUITING
Athens
Alexandra Hospital
RECRUITING
Athens
Attikon University Hospital
RECRUITING
Athens
Henry Dunant Hospital Center
RECRUITING
Athens
Iaso Hospital
RECRUITING
Athens
Metropolitan Hospital
RECRUITING
Athens
Iaso General Clinic
RECRUITING
Marousi
Metaxa Anticancer Hospital
RECRUITING
Piraeus
Agios Loukas Clinic
RECRUITING
Thessaloniki
European Interbalkan Medical Center
RECRUITING
Thessaloniki
Theagenion Cancer Hospital
RECRUITING
Thessaloniki
Hong Kong Special Administrative Region
Queen Mary Hospital, The University of Hong Kong
RECRUITING
Hong Kong
Princess Margaret Hospital
RECRUITING
Kowloon
Queen Elizabeth Hospital, Hong Kong
RECRUITING
Kowloon
Hungary
Budapesti Uzsoki Utcai Korhaz
RECRUITING
Budapest
Orszagos Koranyi Pulmonologiai Intezet
RECRUITING
Budapest
Farkasgyepui Tudogyogyintezet
RECRUITING
Farkasgyepű
Matrai Gyogyintezet
RECRUITING
Gyöngyös
Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktatokorhaz
RECRUITING
Győr
Fejer Varmegyei Szent Gyorgy Egyetemi Oktato Korhaz
RECRUITING
Székesfehérvár
Jasz-Nagykun-Szolnok Varmegyei Hetenyi Geza Korhaz-Rendelointezet
RECRUITING
Szolnok
Komarom-Esztergom Varmegyei Szent Borbala Korhaz
TERMINATED
Tatabánya
Reformatus Pulmonologiai Centrum
RECRUITING
Törökbálint
Italy
IRCCS Istituto Tumori Giovanni Paolo II
RECRUITING
Bari
Azienda Socio Sanitaria Territoriale Spedali Civili di Brescia
RECRUITING
Brescia
Azienda Ospedaliero Universitaria Policlinico G Rodolico - San Marco Presidio Ospedaliero G Rodolico
RECRUITING
Catania
Azienda Ospedaliero Universitaria Careggi
RECRUITING
Florence
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori
RECRUITING
Meldola (fc)
Fondazione IRCCS Istituto Nazionale dei Tumori
RECRUITING
Milan
Fondazione IRCCS San Gerardo dei Tintori
RECRUITING
Monza (mb)
Azienda Ospedaliera di Rilievo Nazionale Specialistica dei Colli Monaldi
RECRUITING
Napoli
Azienda Ospedaliero Universitaria Luigi Vanvitelli
RECRUITING
Napoli
Azienda Ospedaliero-Universitaria di Parma
RECRUITING
Parma
Azienda Ospedaliera di Perugia Ospedale Santa Maria della Misericordia
RECRUITING
Perugia
Azienda Sanitaria Territoriale Pesaro Urbino - Presidio San Salvatore Muraglia
RECRUITING
Pesaro
IRCCS Istituti Fisioterapici Ospitalieri
RECRUITING
Rome
Azienda Sanitaria Universitaria Friuli Centrale Presidio Ospedaliero Santa Maria della Misericordia
RECRUITING
Udine
Japan
Juntendo University Hospital
RECRUITING
Bunkyo-ku
Chiba Cancer Center
RECRUITING
Chiba
National Hospital Organization Kyushu Cancer Center
RECRUITING
Fukuoka
Chugoku Central Hospital of Japan Mutual Aid Association of Public School Teachers
RECRUITING
Fukuyama-shi
Kansai Medical University Hospital
RECRUITING
Hirakata-shi
Hirosaki University Hospital
RECRUITING
Hirosaki-shi
Kanazawa University Hospital
RECRUITING
Kanazawa
National Cancer Center Hospital East
RECRUITING
Kashiwa-shi
St Marianna University Hospital
RECRUITING
Kawasaki-shi
Saitama Cancer Center
RECRUITING
Kitaadachi-gun
Hospital of the University of Occupational and Environmental Health, Japan
RECRUITING
Kitakyushu-shi
Kobe Minimally invasive Cancer Center
RECRUITING
Kobe
The Cancer Institute Hospital of Japanese Foundation for Cancer Research
RECRUITING
Koto-ku
Kurume University Hospital
RECRUITING
Kurume-shi
Kyoto University Hospital
RECRUITING
Kyoto
National Hospital Organization Shikoku Cancer Center
RECRUITING
Matsuyama
Nagoya University Hospital
RECRUITING
Nagoya
Miyagi Cancer Center
RECRUITING
Natori-shi
Niigata Cancer Center Hospital
RECRUITING
Niigata
Okayama University Hospital
RECRUITING
Okayama
Osaka International Cancer Institute
RECRUITING
Osaka
Kindai University Hospital
RECRUITING
Osakasayama-shi
National Hospital Organization Kinki-chuo Chest Medical Center
RECRUITING
Sakai-shi
National Hospital Organization Hokkaido Cancer Center
RECRUITING
Sapporo
Sendai Kousei Hospital
RECRUITING
Sendai
Shizuoka Cancer Center
RECRUITING
Sunto-gun
Takarazuka City Hospital
RECRUITING
Takarazuka-shi
Ehime University Hospital
RECRUITING
Toon-shi
National Hospital Organization Yamaguchi-Ube Medical Center
RECRUITING
Ube-shi
Wakayama Medical University Hospital
RECRUITING
Wakayama
Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center
RECRUITING
Yokohama
Tottori University Hospital
RECRUITING
Yonago-shi
Latvia
Pauls Stradins Clinical University Hospital
RECRUITING
Riga
Riga East Clinical University Hospital
RECRUITING
Riga
Malaysia
Pantai Hospital Kuala Lumpur
RECRUITING
Kuala Lumpur
University Malaya Medical Centre
RECRUITING
Kuala Lumpur
Hospital Tengku Ampuan Afzan
RECRUITING
Kuantan
Mexico
Actualidad Basada en la Investigación del Cáncer
RECRUITING
Guadalajara
Hospital Civil de Guadalajara Fray Antonio Alcalde
RECRUITING
Guadalajara
Health Pharma Professional Research SA de CV
RECRUITING
Mexico City
Hospital Universitario Dr Jose Eleuterio Gonzalez
RECRUITING
Monterrey
Oncare
RECRUITING
Monterrey
Netherlands
Meander Medisch Centrum
RECRUITING
Amersfoort
Universitair Medisch Centrum Groningen
RECRUITING
Groningen
Sint Jansdal Ziekenhuis
RECRUITING
Harderwijk
Maastricht Universitair Medisch Centrum
RECRUITING
Maastricht
Elisabeth-TweeSteden Ziekenhuis
RECRUITING
Tilburg
Isala Klinieken
RECRUITING
Zwolle
Peru
Centro de Investigacion Vallesur
RECRUITING
Arequipa
Hospital de Apoyo Departamental Maria Auxiliadora
RECRUITING
Lima
Oncosalud
RECRUITING
Lima
Unidad de Investigación Clínica Internacional Sede San Borja
RECRUITING
Lima
Poland
Uniwersytecki Szpital Kliniczny w Bialymstoku
RECRUITING
Bialystok
Centrum Pulmonologii i Torakochirurgii w Bystrej
RECRUITING
Bystra
Szpitale Pomorskie spolka z ograniczona odpowiedzialnoscia
RECRUITING
Gdynia
Szpital Specjalistyczny imienia Ludwika Rydygiera w Krakowie Sp zoo
RECRUITING
Krakow
Instytut Centrum Zdrowia Matki Polki
RECRUITING
Lodz
Uniwerystecki Szpital Kliniczny Nr 4 w Lublinie
RECRUITING
Lublin
Med Polonia Sp zoo
RECRUITING
Poznan
Wojewodzki Szpital im Sw Ojca Pio w Przemyslu
RECRUITING
Przemyśl
Specjalistyczny Szpital im Dra Alfreda Sokolowskiego
RECRUITING
Wałbrzych
Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy
RECRUITING
Warsaw
Portugal
Fundacao Champalimaud
RECRUITING
Lisbon
Hospital Cuf Tejo
RECRUITING
Lisbon
Hospital da Luz, SA
RECRUITING
Lisbon
Unidade Local de Saude de Santa Maria, EPE - Hospital Pulido Valente
RECRUITING
Lisbon
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano
RECRUITING
Matosinhos Municipality
Hospital Cuf porto
RECRUITING
Porto
Republic of Korea
Pusan National University Hospital
RECRUITING
Busan
National Cancer Center
RECRUITING
Goyang-si Gyeonggi-do
Gachon University Gil Medical Center
RECRUITING
Incheon
Asan Medical Center
RECRUITING
Seoul
Korea University Anam Hospital
RECRUITING
Seoul
Korea University Guro Hospital
RECRUITING
Seoul
Samsung Medical Center
RECRUITING
Seoul
Pusan National University Yangsan Hospital
RECRUITING
Yangsan-si, Gyeongsangnam-do
Romania
Institutul Oncologic, Prof Dr Alexandru Trestioreanu
RECRUITING
Bucharest
Spitalul Universitar de Urgenta Bucuresti
RECRUITING
Bucharest
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca
RECRUITING
Cluj-napoca
SC Medisprof SRL
RECRUITING
Cluj-napoca
Centrul de Oncologie Sf Nectarie SRL
RECRUITING
Craiova
Institutul Regional de Oncologie Iasi
RECRUITING
Iași
Spitalul Municipal Ploiesti
RECRUITING
Ploieşti
SC Oncomed SRL
RECRUITING
Timișoara
Singapore
National University Hospital
RECRUITING
Singapore
Tan Tock Seng Hospital
RECRUITING
Singapore
Spain
Complexo Hospitalario Universitario A Coruna Hospital Teresa Herrera
RECRUITING
A Coruña
Hospital Clinic i Provincial de Barcelona
RECRUITING
Barcelona
Hospital de la Santa Creu i Sant Pau
RECRUITING
Barcelona
Hospital del Mar
RECRUITING
Barcelona
Hospital Universitari Vall d Hebron
RECRUITING
Barcelona
Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals
RECRUITING
L'hospitalet De Llobregat
Hospital Universitario Insular de Gran Canaria
RECRUITING
Las Palmas De Gran Canaria
Fundacion Jimenez Diaz
RECRUITING
Madrid
Hospital Clinico San Carlos
RECRUITING
Madrid
Hospital Universitario La Paz
TERMINATED
Madrid
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING
Majadahonda
Hospital Regional Universitario de Malaga
RECRUITING
Málaga
Hospital Universitario Marques de Valdecilla
RECRUITING
Santander
Hospital Universitario Virgen del Rocio
RECRUITING
Seville
Hospital Clinico Universitario de Valencia
RECRUITING
Valencia
Hospital Universitari i Politecnic La Fe
RECRUITING
Valencia
Hospital Clinico Universitario Lozano Blesa
RECRUITING
Zaragoza
Sweden
Gavle Sjukhus
RECRUITING
Gävle
Sahlgrenska Universitetssjukhuset
RECRUITING
Gothenburg
Norrlands Universitetssjukhus
RECRUITING
Umeå
Switzerland
Kantonsspital Aarau
TERMINATED
Aarau
Kantonsspital Baden
RECRUITING
Baden
Universitaetsspital Basel
RECRUITING
Basel
Universitaetsspital Zuerich
RECRUITING
Zurich
Taiwan
China Medical University Hospital
RECRUITING
Taichung
Veterans General Hospital - Taichung
RECRUITING
Taichung
Chi Mei Hospital, Liouying
RECRUITING
Tainan City
National Cheng Kung University Hospital
RECRUITING
Tainan City
National Taiwan University Hospital
RECRUITING
Taipei
Taipei Veterans General Hospital
RECRUITING
Taipei
Linkou Chang Gung Memorial Hospital
RECRUITING
Taoyuan District
Thailand
King Chulalongkorn Memorial Hospital
RECRUITING
Bangkok
Phramongkutklao Hospital
RECRUITING
Bangkok
Vajira Hospital
RECRUITING
Bangkok
Maharaj Nakorn Chiang Mai Hospital
RECRUITING
Chiang Mai
Srinagarind Hospital
RECRUITING
Khon Kaen
Banphaeo General Hospital
RECRUITING
Samut Sakhon
Songklanagarind Hospital
RECRUITING
Songkhla
Turkey
Baskent Universitesi Adana Doktor Turgut Noyan Uygulama ve Arastirma Merkezi
RECRUITING
Adana
Medical Park Seyhan Hastanesi
RECRUITING
Adana
Ankara Bilkent Sehir Hastanesi
RECRUITING
Ankara
Gazi Universitesi Saglik Arastirma ve Uygulama Merkezi Gazi Hastanesi
RECRUITING
Ankara
Hacettepe Universitesi Tip Fakultesi Hastanesi
RECRUITING
Ankara
Akdeniz Universitesi Tip Fakultesi
RECRUITING
Antalya
Aydin Adnan Menderes Universitesi Tip Fakultesi
RECRUITING
Aydin
Pamukkale Universitesi Tip Fakultesi Hastanesi
TERMINATED
Denizli
Bagcilar Medipol Mega Universite Hastanesi
RECRUITING
Istanbul
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi
RECRUITING
Istanbul
Istanbul Universitesi Cerrahpasa Tip Fakultesi
RECRUITING
Istanbul
Marmara Universitesi Tip Fakultesi Hastanesi
RECRUITING
Istanbul
Memorial Bahcelievler Hastanesi
RECRUITING
Istanbul
Dr Suat Seren Gogus Hastaliklari ve Cerrahisi Egitim ve Arastirma Hastanesi
RECRUITING
Izmir
Izmir Ekonomi Universitesi Medical Point Hastanesi
RECRUITING
Izmir
Ondokuz Mayis Universitesi Tip Fakultesi Hastanesi
TERMINATED
Samsun
United Kingdom
Queen Elizabeth Hospital Birmingham
RECRUITING
Birmingham
Raigmore Hospital
RECRUITING
Inverness
Royal Marsden Hospital
RECRUITING
London
Mount Vernon Cancer Centre
RECRUITING
Northwood
Nottingham City Hospital
RECRUITING
Nottingham
Royal Marsden Hospital
RECRUITING
Sutton
Torbay Hospital
RECRUITING
Torquay
Royal Cornwall Hospital
RECRUITING
Truro
Contact Information
Primary
Amgen Call Center
medinfo@amgen.com
866-572-6436
Time Frame
Start Date: 2023-11-16
Estimated Completion Date: 2031-06-30
Participants
Target number of participants: 750
Treatments
Experimental: Sotorasib combined with carboplatin and pemetrexed
Sotorasib administered in combination with carboplatin and pemetrexed.
Active_comparator: Pembrolizumab combined with carboplatin and pemetrexed
Pembrolizumab administered in combination with carboplatin and pemetrexed.
Related Therapeutic Areas
Sponsors
Leads: Amgen