Real-World Treatment Patterns and Effectiveness of Targeted and Systemic Therapy in Patients With Advanced Lung Cancer Carrying MET Mutation-Positive

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

This is a descriptive observational study in which data are collected in an epidemiological manner. This study is not intended to alter or interfere with the current medical practice of the enrolled patients. Data will be collected in a forward-looking manner. This is a descriptive observational study in which data are collected in an epidemiological manner. This study is not intended to alter or interfere with the current medical practice of the enrolled patients. Data from patients on prior treatment will be collected retrospectively, and data from patients who will be treated later and included in the study will be collected in a prospective manner. The criteria for retrospective collection were consistent with those for prospective collection. Eligible patients will be enrolled after NGS analysis of tumor tissue and informed consent has been obtained. Information required for the study will be collected (every 3 months).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Patients must be ≥18 years of age.

• Provision of fully informed consent prior to any study specific procedures.

• Histologically or cytologically confirmed, unresectable stage IIIB/IIIC or stage IV NSCLC.

• Genetic variants of tumor tissue detected by NGS.

Locations
Other Locations
China
Hunan Province Tumor Hospital
RECRUITING
Changsha
Contact Information
Primary
Yongchang Zhang, MD
zhangyongchang@csu.edu.cn
+8613873123436
Backup
Nong Yang
yangnong0217@163.com
+8613873123436
Time Frame
Start Date: 2020-01-01
Estimated Completion Date: 2025-06-30
Participants
Target number of participants: 200
Treatments
ICIs
Patients receiving in first-line immunotherapy with or without anti-angiogenic or chemotherapy
Savolitinib
Patients receiving in first-line savolitinib treatment
Glumetinib
Patients receiving in first-line glumetinib treatment
Bozitinib
Patients receiving in first-line bozitinib treatment
Related Therapeutic Areas
Sponsors
Leads: Hunan Province Tumor Hospital

This content was sourced from clinicaltrials.gov