Digital Smoking Cessation Intervention for Nationally-Recruited American Indians and Alaska Natives: A Full-Scale Randomized Controlled Trial

Status: Recruiting
Location: See location...
Intervention Type: Procedure, Other, Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This clinical trial compares a new smoking cessation smartphone application (app) (iCanQuit) to an existing smarphone app (National Cancer Institute \[NCI\] QuitGuide) for helping American Indians and Alaska Natives (AIANs) quit smoking. Compared to other racial/ethnic groups, AIANs have 6 times higher rates of developing smoking-related cancers, including lung cancer. Commercial cigarette smoking accounts for half of all deaths among AIANs nationwide. AIANs' often lack of access to smoking cessation interventions, which may be due to inequities in the healthcare system, lack of health insurance, living in rural areas, systemic racism, and historical trauma. There is also a lack of effective smoking cessation interventions for AIANs. Smartphone apps have the potential to deliver a low-cost smoking cessation intervention with wide reach to AIANs. Apps require no in-person delivery and no provider training, do not require integration into complex hospital systems, can be freely accessed on an app store, and are available at any time and any place. iCanQuit is a behavioral intervention designed to help adults stop smoking by teaching skills for coping with smoking urges, staying motivated, and preventing relapse. The iCanQuit app intervention may be more effective than the currently available NCI QuitGuide app at helping AIANs quit smoking.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Self-identify as American Indian or Alaska Native, either alone or in combination with other races

• Age 18 and older

• Has smoked daily for the past year

• Interest in quitting smoking within the next 30 days

• Willing to be randomly assigned to either app

• Have daily access to their own Android or iPhone

• Able to download a smartphone app

• Be willing and able to read English

• Not currently or within past 30 days using other smoking cessation behavioral interventions or smoking cessation pharmacotherapies

• Have never participated in our prior research

• Have no other household or family member participating

• Being willing to complete the 3, 6, and 12-month follow-up assessments

• Providing email, phone number(s), and mailing address

• Living off United States (US) AIAN tribal reservations or living on five Northern Plains tribal reservations from whom we would obtain approvals to recruit

Locations
United States
Washington
Fred Hutch/University of Washington Cancer Consortium
RECRUITING
Seattle
Contact Information
Primary
Brie Sullivan
bsulliva@fredhutch.org
206-667-5238
Time Frame
Start Date: 2025-07-03
Estimated Completion Date: 2028-11-30
Participants
Target number of participants: 776
Treatments
Experimental: Arm I (iCanQuit app)
Participants use the iCanQuit app, which includes setting up a personalized quit plan, participating in eight levels of the content, receiving on-demand help in coping with smoking urges, and tracking their daily smoking behaviors for at least 45 days on study.
Active_comparator: Arm II (NCI QuitGuide app)
Participants use the NCI QuitGuide app for at least 45 days on study.
Related Therapeutic Areas
Sponsors
Leads: Fred Hutchinson Cancer Center
Collaborators: National Cancer Institute (NCI)

This content was sourced from clinicaltrials.gov