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Exploring the Frontiers of Neoadjuvant Therapy for Lung Cancer: a Prospective Observational Real-world Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Lung cancer is a malignant tumor with the highest incidence and mortality rate of cancer patients worldwide. Traditional treatments for lung cancer include surgery, radiotherapy and chemotherapy, etc. Although the growth and spread of the tumor can be controlled to a certain extent, the cure rate for patients with progressive stage is still low and the prognosis is poor. Neoadjuvant therapy intends to use chemotherapy, immunotherapy, and targeted therapy to reduce the size and load of the tumor before surgery, to improve the surgical resection rate and therapeutic effect. 1. Primary research objective: to explore the therapeutic efficacy of patients with different characteristics under different neoadjuvant therapeutic regimens. 2. Secondary objectives To investigate the strengths and weaknesses of different neoadjuvant regimens in real-world clinical practice, and to investigate the long-term outcomes of patients treated with different regimens.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age greater than or equal to 18 years;

• Pathohistologically confirmed diagnosis of non-small cell lung cancer or small cell lung cancer;

• Received neoadjuvant therapy after diagnosis;

• Written informed consent.

Locations
Other Locations
China
Shanghai Pulmonary Hospital
RECRUITING
Shanghai
Contact Information
Primary
Peng Zhang, Ph.D.
zhangpeng1121@tongji.edu.cn
021-55672180
Backup
Ziyun Shen, M.D.
shenzy94@126.com
021-55672180
Time Frame
Start Date: 2023-12-16
Estimated Completion Date: 2033-12-30
Participants
Target number of participants: 2000
Treatments
Non-small cell lung cancer patients receiving neoadjuvant therapy
Patients diagnosed with non-small cell lung cancer who received neoadjuvant therapy.
Small cell lung cancer patients receiving neoadjuvant therapy
Patients diagnosed with small cell lung cancer who received neoadjuvant therapy.
Related Therapeutic Areas
Sponsors
Leads: Shanghai Pulmonary Hospital, Shanghai, China

This content was sourced from clinicaltrials.gov