Comparison of Clinical Effects of Absorbable and Non-absorbable Suture in Bronchial Sleeve Resection

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Bronchial sleeve resection is performed as an alternative to pneumonectomy for lung cancer patients with centrally located lesions and limited cardiopulmonary reserve. Intraoperative bronchial anastomosis is very complex and difficult, mainly due to the difficulty of suturing and knotting in limited space. There are currently few studies comparing the clinical effects of absorbable and non-absorbable suture in bronchial sleeve resection. So the investigator wants to conduct a prospective study, trying to figure out this problem.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 75
Healthy Volunteers: f
View:

• Age 18 to 75 years old.

• The tumor is located in the opening of bronchus, or the edge of the tumor is less than 2 cm away from the opening of the bronchi, while the distance between the edge of the tumor and the carina is more than 1.5 cm.

• Patients with pathological diagnosis of non-small cell lung cancer.

• No distant metastasis in preoperative clinical evaluation.

• Adequate cardiac function, pulmonary function, liver function and renal function for anesthesia and bronchial sleeve resection.

• American Society of Anesthesiologists (ASA) score: Grade I-III.

• Patients who can coordinate the treatment and research and sign the informed consent.

Locations
Other Locations
China
the Affiliated Hospital of Qingdao University
RECRUITING
Qingdao
Contact Information
Primary
Zhe Wu, PhD
17863934867@163.com
+86 17863934867
Time Frame
Start Date: 2023-02-28
Estimated Completion Date: 2025-12
Participants
Target number of participants: 40
Treatments
Experimental: Absorbable Suture Group
All enrolled patients will accept bronchial sleeve resection and lymphadenectomy. If fast-frozen pathology of the resection margin of bronchus confirms negative, We will use the absorbable sutures for bronchial anastomosis.
Experimental: Non-absorbable Suture Group
All enrolled patients will accept bronchial sleeve resection and lymphadenectomy. If fast-frozen pathology of the resection margin of bronchus confirms negative, We will use the non-absorbable sutures for bronchial anastomosis.
Related Therapeutic Areas
Sponsors
Leads: The Affiliated Hospital of Qingdao University

This content was sourced from clinicaltrials.gov