Snipe Medical First In Human Study

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

A Prospective, open label, multi center, single arm, First in Human study to assess the safety and initial performance of EAS1 system for Irreversible Electroporation (IRE) ablation of lung cancer in subjects eligible for tumor resection

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• Adult male and female subjects (age ≥18 years at the date of informed consent signature)

• Subject is capable and willing to provide an informed consent

• Subjects with a known diagnosis of lung cancer at cT1a-T1c, cN0 stages

• At least one pulmonary tumor (primary or metastasis) ≤ 30 mm in maximal diameter, as confirmed by the latest standard of care imaging (CT/MRI), performed preferably up to 30 days prior to screening

• Subjects who are scheduled or deemed eligible by a thoracic surgeon for lung tumor resection

• Subject is able and willing to comply with the study procedures and visits

• There is ≥ 5mm of nodule-free lung parenchyma between target nodule and pleura or fissure, as confirmed by the latest standard of care imaging (CT/MRI), performed preferably up to 30 days prior to screening

• ECOG 0-1

• Stable doses of concomitant medications for at least four (4) weeks prior to enrollment

Locations
Other Locations
Israel
Meir Medical Center
RECRUITING
Kfar Saba
Spain
University Hospital Complex of Salamanca
RECRUITING
Salamanca
United Kingdom
Royal Brompton Hospital
RECRUITING
London
Contact Information
Primary
Emily Ben Shlomo
emily.benshlomo@clalit.org.il
972523212687
Time Frame
Start Date: 2024-11-01
Estimated Completion Date: 2025-07-15
Participants
Target number of participants: 15
Treatments
Experimental: Treatment Arm - Ablation with EAS1 System
Ablation of the lung tumor via Irreversible Electroporation (IRE) method, followed by resection of the tumor up to 14 days after the ablation
Related Therapeutic Areas
Sponsors
Leads: Snipe Medical

This content was sourced from clinicaltrials.gov

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