The Effects of Programmed Death-ligand 1 on Postoperative Pain for Lung Cancer Patients
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The concentration of plasma programmed death-ligand 1(PD-L1) for lung cancer patients before video-assisted thoracoscopic surgery is detected. According to the distribution of plasma concentration, patients are divided into high or low expression of PD-L1. Differences in acute and chronic postoperative pain are compared between two groups of patients. And effects of PD-L1 expresion on postoperative pain in lung cancer patients are explained.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• American Society of Anesthesiologists physical status I-IV (males and females).
• 18-80 years of age.
• Patients undergoing video-assisted thoracoscopic surgery for malignant lung disease.
Locations
Other Locations
China
Peking University People's Hospital
RECRUITING
Beijing
Contact Information
Primary
Xue Tian, MD
justine_troy@163.com
88325581
Time Frame
Start Date: 2024-07-20
Estimated Completion Date: 2025-03
Participants
Target number of participants: 100
Treatments
high expression of programmed death-ligand 1
According to the distribution of PD-L1 concentration levels in the plasma, participants were divided into two groups: high expression of PD-L1 (PD-L1(H)) and low expression of PD-L1 (PD-L1(L)).
low expression of programmed death-ligand 1
According to the distribution of PD-L1 concentration levels in the plasma, participants were divided into two groups: high expression of PD-L1 (PD-L1(H)) and low expression of PD-L1 (PD-L1(L)).
Related Therapeutic Areas
Sponsors
Leads: Peking University People's Hospital