IMMUNOBLOOD: Perspective Study for the Evaluation of Anti-Inhibitory Checkpoint Antibody Development in Patients Undergoing Immunotherapy

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Non-small cell lung cancer (NSCLC) is one of the leading causes of death in Western countries. Today, a new frontier in the fight against cancer is immunotherapy, a treatment that aims to awaken the patient's immune system to help it recognize and attack cancer cells. Among the various approaches, there is significant focus on therapies that activate T lymphocytes, a type of immune cell, encouraging them to react against the tumor. These treatments have led to important progress and represent a hope for the future.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Histologically or cytologically confirmed diagnosis of NSCLC

• Possibility to obtain blood samples

• Patient candidate, in any therapy line, for a therapy with any checkpoint inhibitor including single agent pembrolizumab, single agent atezolizumab, single agent nivolumab, single agent durvalumab or combination of nivolumab and ipilimumab

• Performance status 0-2 (ECOG)

• Patient compliance to trial procedures

• Age ≥ 18 years

• Written informed consent

Locations
Other Locations
Italy
Istituto Tumori Regina Elena
RECRUITING
Roma
Istituto Tumori Regina Elena
ENROLLING_BY_INVITATION
Roma
Contact Information
Primary
Federico FC Cappuzzo, PI
federico.cappuzzo@ifo.it
+390544285206
Backup
Grisel GM Maver Militello, Monitor
grisel.mavermilitello@ifo.it
0652662724
Time Frame
Start Date: 2021-05-20
Estimated Completion Date: 2025-12
Participants
Target number of participants: 270
Sponsors
Leads: Fondazione Ricerca Traslazionale

This content was sourced from clinicaltrials.gov