Image-Based Functionally Adapted Radiation Therapy for Lung Cancer

Status: Recruiting
Location: See location...
Intervention Type: Other, Drug, Diagnostic test
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

The purpose of this research study is to explore using MRI scans with xenon to better image lung function, how lung function changes after radiation therapy, and to guide radiation therapy away from parts of the lung that have good function. This project is foundational to performing additional studies to establish if novel MRI imaging can serve as a guidance tool for lung cancer radiation treatment.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

⁃ Subjects must meet all of the following inclusion criteria to be eligible for enrollment into the trial

• Aged 18-80 years

• Willing and able to provide informed consent and adhere to visit/protocol schedules (Consent must be given before any study procedures are performed.)

• Clinical diagnosis of lung cancer made by a board-certified oncologist with intent to treat with stereotactic body radiation therapy. We will not exclude individuals based on cancer type or severity of disease with the exception of the below criteria

Locations
United States
Iowa
University of Iowa
RECRUITING
Iowa City
Contact Information
Primary
Eric Bruening
eric-bruening@uiowa.edu
319-789-0806
Time Frame
Start Date: 2025-08
Estimated Completion Date: 2027-01
Participants
Target number of participants: 15
Treatments
Experimental: Technical Development Arm
Lung cancer patients who will undergo standard-of-care stereotactic body radiation therapy (SBRT).
Experimental: Implementation Arm
Lung cancer patients who will undergo SBRT plans that were functionally adapted to avoid highly functioning lung based on Xe MRI.
Related Therapeutic Areas
Sponsors
Leads: Sean Fain

This content was sourced from clinicaltrials.gov