New Markers of Glycation to Predict Gestational Diabetes Mellitus and Macrosomia.
Gestational diabetes mellitus (GDM) increases the risk of macrosomia and other adverse pregnancy outcomes. Screening strategies are debated: universal vs. selective, and macrosomia may begin before the time of screening, suggesting that glycation markers may have an interest. The objective of this trail is to compare novel markers: skin autofluorescence and glycated albumin, to HbA1c (reference) as predictors of GDM, macrosomia and other adverse outcomes, in pregnant women.
• Age ≥ 18 years
• Singleton pregnancy (or twin pregnancy reduced spontaneously or medically before 14 weeks of amenorrhea)
• Gestational age at inclusion \<28 weeks of amenorrhea
• Participant affiliated with or beneficiary of a social security scheme
• Collection of patient consent.