Mood-reactive Habitual Rumination and Changes During Behavioral Activation Treatment for Major Depression

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Depressive rumination, a negative thinking style characterized by repetitive and passive thoughts about the causes, meanings, and consequences of one's feelings and distress, is often described as being a habitual response tendency that forms a vulnerability to depression. Behavioural Activation (BA) is an effective treatment for depression but little is known of mechanisms of changes during a successful treatment completion and for whom the treatment benefits the most. The main purpose of the study is to investigate whether habit-like mood-reactive rumination will change during Behavioral Activation treatment for current depression and mediates symptom changes in the treatment. Important moderators of change will also be investigated (i.e. history of early life stress and cognitive flexibility). We aim to provide individual BA treatment for up to 120 currently depressed participants (from 90 to 120 participants) in 12 treatment sessions over 11 weeks. Measures are obtained at pre-treatment, during treatment, at post-treatment and at 6 month follow up.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Current major depressive episode according to the DSM-5 diagnostic criteria evaluated with the DIAMOND diagnostic interview, that is considered to be the primary diagnosis.

• Sore of 14 or higher on Becks Depression Inventory-II (BDI-II) that measures severity of symptoms of depression past 2 weeks.

• Participants are between 18 and 65 years of age at start of study.

• Satisfactory understanding of the Icelandic language to complete measures in the study.

• Completion of pre-treatment assessment that includes 2 visits to researchers and a 6-day ecological momentary assessment.

Locations
Other Locations
Iceland
University of Iceland
RECRUITING
Reykjavik
Contact Information
Primary
Ragnar P Ólafsson, PhD
ragnarpo@hi.is
8622245
Backup
Sigurður Viðar, Cand.Psych
siv1@hi.is
8641751
Time Frame
Start Date: 2024-02-09
Estimated Completion Date: 2026-02-01
Participants
Target number of participants: 120
Treatments
Experimental: Treatment
Active treatment provided to all participants in the study.
Related Therapeutic Areas
Sponsors
Collaborators: The Icelandic Centre for Research
Leads: Ragnar Pétur Ólafsson

This content was sourced from clinicaltrials.gov