The Effect of Respiratory and Aerobic Exercises on Neuroprotective and Inflammation Biomarkers in Patients Diagnosed With Major Depression
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study aims to investigate changes in the levels of biomarkers (IGF-1, FGF2, and EGF) involved in neuron development in patients diagnosed with major depression through the effects of breathing exercises and aerobic exercise, as well as to examine the levels of biomarkers (TNF-α, IL-6, and IL-1) and oxidative stress (TAS, TOS, MDA, and F2-isoprostane) that are thought to play a role in the pathophysiology of depression.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 40
Healthy Volunteers: f
View:
• Individuals who volunteer to participate in the study,
• Between the ages of 18 and 40,
• Have been diagnosed with clinical depression by a psychiatrist according to DSM-5 criteria
Locations
Other Locations
Turkey
Kutahya Health Sciences University
RECRUITING
Kütahya
Contact Information
Primary
Hatice Solak, Assos. Prof
hatice.solak@ksbu.edu.tr
+90274 260 0043
Backup
Vedat Kurt, Assos. Prof.
vedat.kurt@ksbu.edu.tr
+90 553 3813177
Time Frame
Start Date: 2024-08-01
Estimated Completion Date: 2025-09-30
Participants
Target number of participants: 40
Treatments
Experimental: Exercise Group
Those included in the experimental group continued diaphragmatic breathing exercises every day for three weeks and walking exercises at least three days a week.
No_intervention: Control group
The control group continued their routine lives, and at the end of three weeks
Related Therapeutic Areas
Sponsors
Collaborators: Scientific Research Projects Coordination Unit
Leads: Kutahya Health Sciences University