Learn About Malignant Teratoma of the Mediastinum

What is the definition of Malignant Teratoma of the Mediastinum?

A teratoma is a type of cancer that contains one or more of the three layers of cells found in a developing baby (embryo). These cells are called germ cells. A teratoma is one type of germ cell tumor.

The mediastinum is located inside the front of the chest in the area that separates the lungs. The heart, large blood vessels, windpipe, thymus gland, and esophagus are found there.

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What are the alternative names for Malignant Teratoma of the Mediastinum?

Dermoid cyst - malignant; Nonseminomatous germ cell tumor - teratoma; Immature teratoma; GCTs - teratoma; Teratoma - extragonadal

What are the causes of Malignant Teratoma of the Mediastinum?

Malignant mediastinal teratoma occurs most often in young men in their 20s or 30s. Most malignant teratomas can spread throughout the body, and have spread by the time of diagnosis.

Blood cancers are often associated with this tumor, including:

  • Acute myelogenous leukemia (AML)
  • Myelodysplastic syndromes (group of bone marrow disorders)
What are the symptoms of Malignant Teratoma of the Mediastinum?

Symptoms may include:

  • Chest pain or pressure
  • Cough
  • Fatigue
  • Limited ability to tolerate exercise
  • Shortness of breath
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What are the current treatments for Malignant Teratoma of the Mediastinum?

Chemotherapy is used to treat the tumor. A combination of medicines (usually cisplatin, etoposide, and bleomycin) is commonly used.

After chemotherapy is complete, CT scans are taken again to see if any of the tumor remains. Surgery may be recommended if there is a risk that the cancer will grow back in that area or if any cancer has been left behind.

Who are the top Malignant Teratoma of the Mediastinum Local Doctors?
Elite
Highly rated in
32
conditions
Urology

Keck Medicine of USC

Beverly Hills - Urology

9033 Wilshire Blvd 
Beverly Hills, CA 90211

Siamak Daneshmand is an Urologist in Beverly Hills, California. Dr. Daneshmand has been practicing medicine for over 26 years and is rated as an Elite doctor by MediFind in the treatment of Malignant Teratoma of the Mediastinum. He is also highly rated in 32 other conditions, according to our data. His top areas of expertise are Bladder Cancer, Cystectomy, Urothelial Cancer, and Muscle Invasive Bladder Cancer. He is licensed to treat patients in California. Dr. Daneshmand is currently accepting new patients.

Elite
Highly rated in
14
conditions
Hematology Oncology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Darren Feldman is a Hematologist Oncology doctor in New York, New York. Dr. Feldman has been practicing medicine for over 21 years and is rated as an Elite doctor by MediFind in the treatment of Malignant Teratoma of the Mediastinum. He is also highly rated in 14 other conditions, according to our data. His top areas of expertise are Testicular Cancer, Malignant Teratoma of the Mediastinum, Chromophobe Renal Cell Carcinoma, and Renal Cell Carcinoma RCC. He is licensed to treat patients in New York. Dr. Feldman is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
11
conditions
Urology

Memorial Sloan Kettering Cancer Center

1275 York Ave 
New York, NY 10065

Joel Sheinfeld is an Urologist in New York, New York. Dr. Sheinfeld has been practicing medicine for over 41 years and is rated as an Elite doctor by MediFind in the treatment of Malignant Teratoma of the Mediastinum. He is also highly rated in 11 other conditions, according to our data. His top areas of expertise are Testicular Cancer, Malignant Teratoma of the Mediastinum, Choriocarcinoma, and Scrotal Masses. He is licensed to treat patients in New York. Dr. Sheinfeld is currently accepting new patients.

What are the support groups for Malignant Teratoma of the Mediastinum?

There are many support groups available for people with cancer. Contact the American Cancer Society -- www.cancer.org.

What is the outlook (prognosis) for Malignant Teratoma of the Mediastinum?

The outlook depends on the tumor size and location and the age of the patient.

What are the possible complications of Malignant Teratoma of the Mediastinum?

The cancer can spread throughout the body and there may be complications of surgery or related to chemotherapy.

When should I contact a medical professional for Malignant Teratoma of the Mediastinum?

Call your provider if you have symptoms of malignant teratoma.

Teratoma - MRI scan
Malignant teratoma
What are the latest Malignant Teratoma of the Mediastinum Clinical Trials?
Imaging of Patients With Malignant Brain Tumors Using 89Zr-cRGDY Ultrasmall Silica Particle Tracers: A Phase 1 Microdosing Study
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Clinical Investigation to Evaluate the CONVIVO System for Discrimination of Normal From Abnormal Tissue During Brain Tumor Resection
What are the Latest Advances for Malignant Teratoma of the Mediastinum?
Postchemotherapy retroperitoneal residual mass resection for germ cell testicular tumors: a single-center experience.
Outcomes and prognostic variables of extracranial germ cell tumors in children and adolescents treated over a decade: A developing world perspective.
Tired of the same old research?
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Robotic-assisted thoracoscopic resection of anterior mediastinal cystic teratoma: a case report and literature review.
Who are the sources who wrote this article ?

Published Date : July 28, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Cheng G-S, Varghese TK, Park DR. Mediastinal tumors and cysts. In: Broaddus VC, Mason RJ, Ernst JD, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 6th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 83.

Putnam JB. Lung, chest wall, pleura, and mediastinum. In: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Textbook of Surgery. 20th ed. Philadelphia, PA: Elsevier; 2017:chap 57.