Effect of Fermented Millet Porridge on Gut Microbiota Diversity and Inflammation Markers in Women of Reproductive Age in Rural Burkina Faso: A Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Maternal undernutrition concerns 10-19% of women of reproductive age globally, the vast majority of which live in sub Saharan Africa and south Asia. Recommendations for nutritional interventions to tackle the problem range from per-pregnancy supplementation to upstream interventions targeting women of reproductive age before conception. To render the latter interventions cost-effective and sustainable, experts recommend to focus on food processing that leads to an enhanced nutrient content. One such method, which has been known and practiced for centuries in diverse societies, is fermentation. Traditionally fermented foods are diverse, widespread and highly appreciated in Burkina Faso. The present study aims to investigate the effect of fermented millet porridge on gut microbiota diversity, stool short chain fatty acid concentration and inflammation markers level in women of reproductive age living in rural Burkina Faso.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 49
Healthy Volunteers: t
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⁃ Participant are

• 18 to 49 years old

• Resident in the study area and do not plan to move within 5 months following the start of the study

• Are not on antibiotic treatment on inclusion and have not been in the previous 3 weeks.

• Do not suffer from any pathology that could interfere with their diet.

• Have no known allergy to pearl millet or its derivatives

• Agree to sign a consent to participate in the study-

Locations
Other Locations
Burkina Faso
IRSS-DRO
RECRUITING
Bobo-dioulasso
Contact Information
Primary
Laeticia C TOE, MD
cellaety@yahoo.fr
0022671007272
Backup
Lionel O Ouedraogo
lionel.olivier.ouedraogo@gmail.com
0022670530583
Time Frame
Start Date: 2022-03-21
Estimated Completion Date: 2024-07-31
Participants
Target number of participants: 80
Treatments
Experimental: fermented porridge
this study arm participant will consume fermented millet porridge, daily
Active_comparator: Non-fermented porridge
this study arm participants will consume non-fermented millet porridge, daily
Related Therapeutic Areas
Sponsors
Collaborators: Bill and Melinda Gates Foundation, University Ghent
Leads: Institut de Recherche en Sciences de la Sante, Burkina Faso

This content was sourced from clinicaltrials.gov