Efficacy and Safety of Family Mid-upper Arm Circumference (MUAC) After Recovery From Severe and Moderate Acute Malnutrition

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Protocols for the community-based management of acute malnutrition (CMAM) have not changed significantly for more than 20 years, with relatively complex treatment protocols and persistent supply chain challenges that have limited overall program coverage, leaving millions of malnourished children without care annually. The overarching goal of this research project is to simultaneously test two novel simplified approaches in CMAM with potential to improve program coverage. The simplified approach includes two parallel clinical trials for SAM and MAM treatment. For the Family MUAC follow-up study, children who recover from these two parallel clinical trials will be enrolled in trial to test the effectiveness of MUAC screening at home by the child's caregivers as a self-referral strategy, compared to a scheduled health facility-led strategy and the standard of care of community-based follow-up visits.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 6 months
Maximum Age: 4
Healthy Volunteers: f
View:

• children 6-59 months of old who recovered from SAM or MAM following treatment in either the MODAM-SAM or MODAM-MAM trials

Locations
Other Locations
Ethiopia
Gode
RECRUITING
Gode
Sekota
NOT_YET_RECRUITING
Sekota
Teltele
RECRUITING
Teltelē
Contact Information
Primary
Indi Trehan
itrehan@uw.edu
+12067696068
Time Frame
Start Date: 2023-09-25
Estimated Completion Date: 2026-09-25
Participants
Target number of participants: 3600
Treatments
Active_comparator: Control Group
nutrition, IYCF, and WASH education at discharge, followed by regular community-based screenings led by health extension workers, with one final visit scheduled at 6 months after discharge
Active_comparator: scheduled followup
standard of care plus scheduled follow-up visits at 1 month, 3 months, 6 months after discharge
Experimental: family MUAC
standard of care plus Family MUAC training for the primary caregiver present at the time of recovery, with one final visit scheduled at 6 months after discharge
Related Therapeutic Areas
Sponsors
Collaborators: University of Washington, Ethiopian Public Health Institute
Leads: Action Against Hunger USA

This content was sourced from clinicaltrials.gov