The Improvement Effect of Vitamin D on the Cardiovascular Health of Overweight/Obesity Adolescents in China
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency. The main question it aims to answer whether vitamin D3 supplementation can improve cardiovascular metabolic health. Participants in the intervention group will receive vitamin D3. The control group will receive vitamin D placebo. Researchers will compare the change in cardiometabolic risk from baseline to post-intervention at 12 weeks between the intervention and control groups.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 10
Maximum Age: 16
Healthy Volunteers: f
View:
• Students whose caregivers signed informed consents;
• Students with serum 25(OH)D concentration of 12-20 ng/mL;
• Students with overweight or obesity.
Locations
Other Locations
China
Anhui Medical University
RECRUITING
Anqing
Anhui Medical University
RECRUITING
Hefei
Contact Information
Primary
Puyu Su, PhD
supuyu@ahmu.edu.cn
86-13856058551
Backup
Puyu Su, Professor
supuyu@ahmu.edu.cn
86-13856058551
Time Frame
Start Date: 2025-09-15
Estimated Completion Date: 2025-12-31
Participants
Target number of participants: 130
Treatments
Experimental: Experimental
Vitamin D3:~Vitamin D3: 2000 IU per day for 6 weeks (two capsules of 800 IU plus one capsule of 400 IU), followed by 800 IU (one capsule of 800 IU) per day for 6 weeks.
Placebo_comparator: Placebo Comparator
Vitamin D3 placebo:~Vitamin D3 placebo (i.e., soybean oil).
Related Therapeutic Areas
Sponsors
Leads: Anhui Medical University