• ≥ 18 years old.

• Histopathologically confirmed MCL expressing Cyclin D1 and/or t (11;14) chromosomal translocation.Formalin-fixed paraffin-embedded (FFPE) tissues or sections for diagnosis must be provided. It is for the approval of pathological diagnosis by the central pathology laboratory.

• The patient was diagnosed with relapsed or refractory mantle cell lymphoma, and the previous treatment needs to meet the following requirements:

‣ Failure of at least one adequate prior line of anti-CD20-containing therapy;

⁃ Failure of at least one adequate prior line of BTK inhibitor (BTKi)-containing therapy.

• Failure of the last line of therapy.

• At least one measurable lesion according to the Lugano 2014 criteria,.

• ECOG performance status of 0-2 .